René Roy

TL;DR: Galectin-3 is unique among the Galectin family of animal lectins in its biological activities and structure as mentioned in this paper, it possesses anti-apoptotic activity and its kinetics of precipitation are fast, on the order of seconds.

TL;DR: The large-scale synthesis, pharmaceutical development, and clinical evaluation of a conjugate vaccine composed of a synthetic capsular polysaccharide antigen of Haemophilus influenzae type b (Hib) demonstrate that access to synthetic complex carbohydrate–based vaccines is feasible and provides a basis for further development of similar approaches for other human pathogens.

TL;DR: This chapter briefly surveys the concept of multivalency involved in carbohydrate–protein interactions and discusses in regard to recent steps undertaken in glycobiology toward identification of lead candidates using microarrays and modern analytical tools.

TL;DR: The synthesis of other neoglycoconjugates with various shapes, valencies, and conformations has reached considerable levels of sophistication and holds promise as a new tool for glycobiology and biomedical applications as mentioned in this paper.

TL;DR: Significant (p < 0.001) dose-dependent reduction of influenza infection in mammalian cells by polymeric inhibitors is demonstrated, the first such demonstration for multivalent SA inhibitors.