R
Riccardo Candido
Researcher at University of Melbourne
Publications - 58
Citations - 3429
Riccardo Candido is an academic researcher from University of Melbourne. The author has contributed to research in topics: Diabetes mellitus & Angiotensin II. The author has an hindex of 25, co-authored 56 publications receiving 3212 citations. Previous affiliations of Riccardo Candido include University of Trieste & Baker IDI Heart and Diabetes Institute.
Papers
More filters
Journal ArticleDOI
A Breaker of Advanced Glycation End Products Attenuates Diabetes-Induced Myocardial Structural Changes
Riccardo Candido,Josephine M. Forbes,Merlin C. Thomas,Vicki Thallas,Rachael G Dean,Wendy C. Burns,Christos Tikellis,Rebecca H. Ritchie,Stephen M. Twigg,Mark E. Cooper,Louise M Burrell +10 more
TL;DR: It is suggested that AGEs play a central role in many of the alterations observed in the diabetic heart and that cleavage of preformed AGE crosslinks with ALT‐711 leads to attenuation of diabetes‐associated cardiac abnormalities in rats.
Journal ArticleDOI
Advanced glycation end product-interventions reduce diabetes-accelerated atherosclerosis
Josephine M. Forbes,Louis Teo Loon Yee,Vicki Thallas,Markus Lassila,Riccardo Candido,Karin Jandeleit-Dahm,Merlin C. Thomas,Wendy C. Burns,Elizabeth K. Deemer,Susan R. Thorpe,Mark E. Cooper,Terri J. Allen +11 more
TL;DR: AlT-711 and AG demonstrated the ability to reduce vascular AGE accumulation in addition to attenuating atherosclerosis in these diabetic mice.
Journal ArticleDOI
Improved islet morphology after blockade of the renin-angiotensin system in the ZDF rat
Chris Tikellis,Peter J. Wookey,Riccardo Candido,Sofianos Andrikopoulos,Sofianos Andrikopoulos,Merlin C. Thomas,Mark E. Cooper +6 more
TL;DR: Improvements in structural parameters were also associated with functional improvements in first-phase insulin secretion and provide a possible mechanism for the reduced incidence of new-onset diabetes that has been observed in clinical trials of RAS blockade.
Journal ArticleDOI
Prevention of Accelerated Atherosclerosis by Angiotensin-Converting Enzyme Inhibition in Diabetic Apolipoprotein E–Deficient Mice
Riccardo Candido,Karin Jandeleit-Dahm,Zemin Cao,Stefan P. Nesteroff,Wendy C. Burns,Stephen M. Twigg,Rodney J. Dilley,Mark E. Cooper,Terri J. Allen +8 more
TL;DR: The activation of the local renin-angiotensin system in the diabetic aorta and the reduction in atherosclerosis with ACE inhibitor treatment provides further evidence that the ren in-angiotsin system plays a pivotal role in the development and acceleration of atherosclerotic lesions in diabetes.
Journal ArticleDOI
Irbesartan but Not Amlodipine Suppresses Diabetes-Associated Atherosclerosis
Riccardo Candido,Terri J. Allen,Markus Lassila,Zemin Cao,Vicki Thallas,Mark E. Cooper,Karin Jandeleit-Dahm +6 more
TL;DR: Diabetes-associated Atherosclerosis is ameliorated by AT1 receptor blockade but not by calcium channel antagonism, providing further evidence for the vascular renin-angiotensin system playing a pivotal role in the development and acceleration of atherosclerosis in diabetes.