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Rebecca H. Ritchie
Researcher at Monash University
Publications - 168
Citations - 6679
Rebecca H. Ritchie is an academic researcher from Monash University. The author has contributed to research in topics: Diabetic cardiomyopathy & Diabetes mellitus. The author has an hindex of 41, co-authored 150 publications receiving 5332 citations. Previous affiliations of Rebecca H. Ritchie include College of Osteopathic Medicine of the Pacific & Monash University, Parkville campus.
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Journal ArticleDOI
Diabetic cardiomyopathy: Mechanisms and new treatment strategies targeting antioxidant signaling pathways
Karina Huynh,Bianca C. Bernardo,Julie R. McMullen,Julie R. McMullen,Rebecca H. Ritchie,Rebecca H. Ritchie +5 more
TL;DR: This work reviews the current evidence of molecular disturbances present in the diabetic heart, and their role in the development of diabetes-induced impairments in myocardial function and structure, and incorporates both the contribution of increased reactive oxygen species production and reduced antioxidant defenses to diabetic cardiomyopathy.
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A Breaker of Advanced Glycation End Products Attenuates Diabetes-Induced Myocardial Structural Changes
Riccardo Candido,Josephine M. Forbes,Merlin C. Thomas,Vicki Thallas,Rachael G Dean,Wendy C. Burns,Christos Tikellis,Rebecca H. Ritchie,Stephen M. Twigg,Mark E. Cooper,Louise M Burrell +10 more
TL;DR: It is suggested that AGEs play a central role in many of the alterations observed in the diabetic heart and that cleavage of preformed AGE crosslinks with ALT‐711 leads to attenuation of diabetes‐associated cardiac abnormalities in rats.
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Androgen Receptors Mediate Hypertrophy in Cardiac Myocytes
James D. Marsh,Michael H. Lehmann,Rebecca H. Ritchie,Judith K. Gwathmey,Judith K. Gwathmey,Glenn E. Green,R. J. Schiebinger +6 more
TL;DR: Androgen receptors are present in cardiac myocytes from multiple species, including normal men and women, in a context that permits androgens to modulate the cardiac phenotype and produce hypertrophy by direct, receptor-specific mechanisms.
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Nitroxyl (HNO): the Cinderella of the nitric oxide story
Jennifer C Irvine,Rebecca H. Ritchie,Joanne L Favaloro,Karen L. Andrews,Robert E Widdop,Barbara K Kemp-Harper +5 more
TL;DR: HNO donors are protective in the setting of heart failure in which NO donors have minimal impact and the therapeutic potential of HNO donors in the treatment of cardiovascular disease is highlighted.
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Basic Mechanisms of Diabetic Heart Disease
Rebecca H. Ritchie,E. Dale Abel +1 more
TL;DR: The need for continued interrogation of these mechanisms is essential to not only decipher the how and why of diabetes mellitus-induced heart failure but also to facilitate improved inroads into the clinical management of this pervasive clinical challenge.