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Richard H. Bruce
Researcher at PARC
Publications - 62
Citations - 2641
Richard H. Bruce is an academic researcher from PARC. The author has contributed to research in topics: Circulating tumor cell & Breast cancer. The author has an hindex of 21, co-authored 62 publications receiving 2562 citations. Previous affiliations of Richard H. Bruce include SRI International & Scripps Research Institute.
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Proceedings ArticleDOI
Liveboard: a large interactive display supporting group meetings, presentations, and remote collaboration
Scott A. Elrod,Richard H. Bruce,Rich Gold,David E. Goldberg,Frank G. Halasz,William J. Janssen,David Haldane Lee,Kim McCall,Elin Rønby Pedersen,Ken Pier,John C. Tang,Brent B. Welch +11 more
TL;DR: With nearly one million pixels and an accurate, multi-state, cordless pen, the Liveboard provides a basis for research on user interfaces for group meetings, presentations and remote collaboration.
Journal ArticleDOI
A rare-cell detector for cancer
Robert T. Krivacic,Andras Ladanyi,Douglas N. Curry,H.B. Hsieh,Peter Kuhn,Danielle E. Bergsrud,Jane F. Kepros,Todd Barbera,Michael Y. Ho,Lan Bo Chen,Richard A. Lerner,Richard H. Bruce +11 more
TL;DR: An approach that uses fiber-optic array scanning technology (FAST), which applies laser-printing techniques to the rare-cell detection problem, resulting in a 500-fold speed-up over ADM with comparable sensitivity and superior specificity.
Journal ArticleDOI
High speed detection of circulating tumor cells
H. Ben Hsieh,Dena Marrinucci,Kelly Bethel,Kelly Bethel,Douglas N. Curry,Mark Humphrey,Robert T. Krivacic,Joan Kroener,Lindsay Kroener,Andras Ladanyi,Nicole Hanson Lazarus,Peter Kuhn,Richard H. Bruce,Jorge Nieva,Jorge Nieva +14 more
TL;DR: The FAST cytometer was used to detect, image and re-image circulating tumor cells in peripheral blood of breast cancer patients and has the potential to serve as a clinically useful point-of-care diagnostic and a prognostic tool for cancer clinicians.
Journal ArticleDOI
Case study of the morphologic variation of circulating tumor cells.
Dena Marrinucci,Kelly Bethel,Kelly Bethel,Richard H. Bruce,Douglas N. Curry,Ben Hsieh,Mark Humphrey,Robert T. Krivacic,Joan Kroener,Lindsay Kroener,Andras Ladanyi,Nicole Hanson Lazarus,Jorge Nieva,Jorge Nieva,Peter Kuhn +14 more
TL;DR: A detailed cytomorphologic evaluation of the circulating component of widely metastatic breast carcinoma of a previously healthy 38-year-old woman finds that the patient's CTCs exhibit a high degree of pleomorphism including C TCs with high and low nuclear-to-cytoplasmic ratios along with CTCS exhibiting early and late apoptotic changes.
Journal ArticleDOI
Enthalpy arrays
Francisco E. Torres,Peter Kuhn,Dirk De Bruyker,Alan G. Bell,Michal V. Wolkin,Eric Peeters,James R. Williamson,Gregory B. Anderson,Gregory P. Schmitz,Michael I. Recht,Sandra Schweizer,Lincoln G. Scott,Jackson Ho,Scott A. Elrod,Peter G. Schultz,Richard A. Lerner,Richard H. Bruce +16 more
TL;DR: The utility of the enthalpy arrays is demonstrated by showing measurements for two protein-ligand binding interactions, phosphorylation of glucose by hexokinase, and respiration of mitochondria in the presence of 2,4-dinitrophenol uncoupler.