Richard J. Lipscombe

TL;DR: The functional composition of the experimentally derived proteome is similar to that of other scorpions, and contains a potent mix of toxins, antimicrobials and ionic channel inhibitors.

TL;DR: Novel plasma biomarkers that may improve the prediction of rapid decline in renal function independently of recognized clinical risk factors in type 2 diabetes are identified and contributed to improved model performance in predicting other indices of rapid eGFR decline.

TL;DR: 2D LC MALDI-MS/MS is a powerful, rapid and economical tool to aid in the annotation of fungal genomic assemblies.

TL;DR: Comparing the depth and reproducibility of total proteome and differentially expressed protein coverage in technical duplicates and triplicates using iTRAZ 4-plex, iTRAQ 8-plex and TMT 6-plex reagents demonstrates the advantages of using iTraQ 4- Plex reagents over iTRAq 8-Plex and T MT 6-Plex reagents, provides estimates of technical duplicate andTriplicate reproducible, and emphasizes the value of running replicate samples.

TL;DR: Proteomics and metabolomics provide further support for the hypothesis that necrotrophic pathogens, such as S. nodorum, appear to exploit existing host cell death mechanisms to promote pathogen growth and cause disease.