R
Richard L. Eckert
Researcher at University of Maryland, Baltimore
Publications - 220
Citations - 11690
Richard L. Eckert is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Involucrin & Keratinocyte. The author has an hindex of 58, co-authored 211 publications receiving 10996 citations. Previous affiliations of Richard L. Eckert include Harvard University & Case Western Reserve University.
Papers
More filters
Journal ArticleDOI
S100 Proteins in the Epidermis
TL;DR: S100 proteins are of interest as mediators of calcium-associated signal transduction and undergo changes in subcellular distribution in response to extracellular stimuli and may play a role in the pathogenesis of epidermal disease, as selected S100 protein genes are markedly overexpressed in psoriasis, wound healing, skin cancer, inflammation, cellular stress, and other epidersmal states.
Journal ArticleDOI
Structure and evolution of the human involucrin gene
Richard L. Eckert,Howard Green +1 more
TL;DR: The evolution of involucrin as a substrate of transglutaminase and an envelope precursor was evidently made possible by this process of repeated mutation and duplication.
Journal ArticleDOI
The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation
TL;DR: The marker genes that have been utilized to study the process of gene regulation in epidermis are described and the structure and function of the proteins that are thought to be precursors of this structure are discussed.
Journal ArticleDOI
Transglutaminase Regulation of Cell Function
Richard L. Eckert,Mari T. Kaartinen,Maria Nurminskaya,Alexey M. Belkin,Gozde Colak,Gail V.W. Johnson,Kapil Mehta +6 more
TL;DR: The studies described herein begin to clarify the physiological roles of TGs in both normal biology and disease states and highlight the mechanism of action of these proteins with respect to their structure, impact on cell differentiation and survival, role in cancer development and progression.
Journal ArticleDOI
Structure, function, and differentiation of the keratinocyte
TL;DR: Ce travail expose les connaissances acquises acquises concernant la differenciation des Keratinocytes et decrit ce qu'on sait au sujet de la fonction des macromolecules cle exprimees lors oficiaisons.