Richard Veyrat-Masson

TL;DR: A means of identifying subsets containing all the CFU-F and sufficiently enriched to detect them in fresh BM, enabling evaluation of mesenchymal content of BM collections for cell therapy.

TL;DR: A method to evaluate the quality of initial mesenchymal content and track the modifications induced by graft processing has not yet been proposed and a satisfactory correlation between immuno‐phenotyping and functional tests by low‐density plating is established.

TL;DR: For most therapeutic strategies using MSC, the preliminary amplification is carried out in media containing fetal calf serum (FCS) while amplification using human serum (HS) remains controversial at present, the available information on multipotentiality, self-renewal, and transplantability does not permit the selection of FCS rather than HS as discussed by the authors.

TL;DR: In this article, the authors assessed the value of KIR phenotyping and targeted high-throughput sequencing in a cohort of 114 consecutive patients with chronic lymphoproliferative disorders of NK cells (CLPD-NK) and developed an NK-cell clonality score combining flow cytometry and molecular profiling.

TL;DR: VEGF may be a positive autocrine in vivo regulator of MCL-1 in B-CLL and inhibition of VEGF and its signaling may prove to be useful in the treatment of B- CLL patients.