R
Risau Werner
Researcher at Hebrew University of Jerusalem
Publications - 5
Citations - 1621
Risau Werner is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Vascular endothelial growth factor A & Vascular endothelial growth factor C. The author has an hindex of 3, co-authored 5 publications receiving 1601 citations.
Papers
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Journal Article
SU5416 Is a Potent and Selective Inhibitor of the Vascular Endothelial Growth Factor Receptor (Flk-1/KDR) That Inhibits Tyrosine Kinase Catalysis, Tumor Vascularization, and Growth of Multiple Tumor Types
T. A. T. Fong,Laura K. Shawver,Li Sun,Cho Tang,H. App,T. J. Powell,Y. H. Kim,Randall E. Schreck,Xueyan Wang,Risau Werner,Axel Ullrich,K. P. Hirth,Gerald McMahon +12 more
TL;DR: Findings support that pharmacological inhibition of the enzymatic activity of the vascular endothelial growth factor receptor represents a novel strategy for limiting the growth of a wide variety of tumor types.
Journal Article
Flk-1 as a Target for Tumor Growth Inhibition
Laurie M. Strawn,Gerald McMahon,H. App,Schreck R,Kuchler Wr,Michael P. Longhi,Hui Th,C. Tang,Alexander Levitzki,Aviv Gazit,Chen I,György Kéri,Laszlo Orfi,Risau Werner,Flamme I,Axel Ullrich,K. P. Hirth,Laura K. Shawver +17 more
TL;DR: Antiangiogenesis compounds that inhibit Flk-1 tyrosine kinase activity, endothelial cell mitogenesis, and blood vessel formation in the chorioallantoic membrane assay have been found.
Patent
Flk-1 is a receptor for vascular endothelial growth factor
TL;DR: In this paper, the use of ligands for the Flk-1 receptor for the modulation of angiogenesis and vasculogenesis is discussed, based on the demonstration that Flk1 tyrosine kinase receptor expression is associated with endothelial cells and identification of vascular endothelial growth factor (VEGF) as the high affinity ligand of Flk 1.
Patent
Flk-1 UTILISE COMME RECEPTEUR POUR FACTEUR DE CROISSANCE ENDOTHELIAL VASCULAIRE
TL;DR: In this article, le role predominant du recepteur kinase tyrosine Flk-1 dans le systeme de signalisation au cours de la vasculogenese et de l'angiogenese is discussed.