C
C. Tang
Researcher at Pfizer
Publications - 3
Citations - 550
C. Tang is an academic researcher from Pfizer. The author has contributed to research in topics: Autocrine signalling & Growth factor receptor inhibitor. The author has an hindex of 3, co-authored 3 publications receiving 543 citations.
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Journal Article
Flk-1 as a Target for Tumor Growth Inhibition
Laurie M. Strawn,Gerald McMahon,H. App,Schreck R,Kuchler Wr,Michael P. Longhi,Hui Th,C. Tang,Alexander Levitzki,Aviv Gazit,Chen I,György Kéri,Laszlo Orfi,Risau Werner,Flamme I,Axel Ullrich,K. P. Hirth,Laura K. Shawver +17 more
TL;DR: Antiangiogenesis compounds that inhibit Flk-1 tyrosine kinase activity, endothelial cell mitogenesis, and blood vessel formation in the chorioallantoic membrane assay have been found.
Journal Article
Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide.
Laura K. Shawver,D P Schwartz,E Mann,Hui Chen,J Tsai,L M Chu,L Taylorson,Michael P. Longhi,Stephen C. Meredith,L L Germain,J S Jacobs,C. Tang,Axel Ullrich,Michael E. Berens,Evan M. Hersh,Gerald McMahon,K. P. Hirth,T. J. Powell +17 more
TL;DR: SU101 is an effective inhibitor of PDGF-driven tumor growth in vivo and prevents tumor growth and induced long-term survivors in animals implanted with 7TD1 (murine B-cell hybridoma) tumor cells.
Journal ArticleDOI
Growth inhibition of psoriatic keratinocytes by quinazoline tyrosine kinase inhibitors.
T.J. Powell,H. Ben-Bassat,B.Y. Klein,H. Chen,N. Shenoy,J. Mccollough,B. Narog,Aviv Gazit,Z. Harzstark,M. Chaouat,R. Levitzki,C. Tang,J. Mcmahon,Laura K. Shawver,Alexander Levitzki +14 more
TL;DR: SU5271 inhibited the proliferation of keratinocytes isolated from psoriatic lesions in excellent correlation with its EGFR kinase inhibitory activity in these cells, suggesting that this compound is a strong candidate as an antipsoriatic agent.