Robert A. Farley

TL;DR: Evidence that expression of both a and β subunits is required for Na,K‐ATPase activity, that inhibition of glycosylation causes a decrease in accumulation of both α andβ subunits, and evidence that pretranslational up‐regulation of β alone can lead to increased abundance of sodium pumps are provided are consistent with the hypothesis that the β subunit regulates.

TL;DR: The labeling of (Na,K)-ATPase by fluorescein 5'-isothiocyanate was associated with the irreversible inhibition of enzymatic activity, and both the labeling of the tryptic peptide and inhibition of activity were prevented when the reaction was performed in the presence of ATP.

TL;DR: Observations demonstrate that both the alpha subunit and the beta subunit of Na,K-ATPase are required for the expression of functional Na, K- ATPase activity and that yeast cells can correctly assemble this oligomeric membrane protein and transport it to the cell surface.

TL;DR: DMC increases intracellular free calcium levels and potently triggers the ESR in various tumor cell lines, as indicated by transient inhibition of protein synthesis, activation of ER stress–associated proteins GRP78/BiP, CHOP/GADD153, and caspase-4, and subsequent tumor cell death.

TL;DR: The results clearly indicate significant differences in RBC aggregability among the three species and indicate that cellular factors contribute importantly to these differences.