scispace - formally typeset
R

Robert B. Innis

Researcher at National Institutes of Health

Publications -  468
Citations -  34412

Robert B. Innis is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Radioligand & Dopamine. The author has an hindex of 90, co-authored 455 publications receiving 32492 citations. Previous affiliations of Robert B. Innis include Yale University & Veterans Health Administration.

Papers
More filters
Journal ArticleDOI

Hemi-parkinsonism due to a midbrain arteriovenous malformation: dopamine transporter imaging.

TL;DR: The results of dopamine transporter imaging in a patient with hemi-parkinsonism with a history of repeated hemorrhages due to a midbrain arteriovenous malformation treated with radiation are presented.
Journal ArticleDOI

Image-derived input function derived from a supervised clustering algorithm: methodology and validation in a clinical protocol using [11C](R)-rolipram.

TL;DR: Cluster-IDIF showed widespread decrease of about 20% [11C](R)-rolipram binding in the MDD group, suggesting that cluster- IDIF is a good alternative to full arterial input function for estimating Logan-V T/f P in [ 11C]-R-roliprams PET clinical scans.
Journal ArticleDOI

Investigation of the metabolites of (S,S)-[(11)C]MeNER in humans, monkeys and rats.

TL;DR: It can be concluded that radiometabolites of (S,S)-[11C]MeNER are minor importance in humans, and plasma reverse-phase radiochromatographic analysis was performed to monitor and quantify its rate of metabolism.
Journal ArticleDOI

[¹¹C]Rhodamine-123: synthesis and biodistribution in rodents.

TL;DR: Rhodamine-123 was unpromising as a PET probe for P-gp function and appears to be a strong substrate of OCT in kidney in vivo.
Journal ArticleDOI

SPECT imaging of the benzodiazepine receptor: autoradiographic comparison of receptor density and radioligand distribution.

TL;DR: The ex vivo autoradiograms provided quantitative data from a realistic “biological phantom,” which may be used to assess the accuracy of image reconstruction and to investigate differences between the distribution of an intravenously administered tracer and that of its target in brain tissue.