R
Robert Bozsak
Researcher at Dresden University of Technology
Publications - 2
Citations - 408
Robert Bozsak is an academic researcher from Dresden University of Technology. The author has contributed to research in topics: Beta (finance) & Beta cell. The author has an hindex of 2, co-authored 2 publications receiving 259 citations.
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Journal ArticleDOI
Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis
TL;DR: In type 1 and type 2 diabetes impairment of beta cell function is an early feature of disease pathogenesis while a substantial decrease in beta cell mass occurs more closely to clinical manifestation, which suggests that the development of novel strategies for protection and recovery ofBeta cell function could be most promising for successful diabetes treatment and prevention.
Journal ArticleDOI
Dysfunction of Persisting β Cells Is a Key Feature of Early Type 2 Diabetes Pathogenesis.
Christian M. Cohrs,Julia K. Panzer,Denise M. Drotar,Stephen J. Enos,Nicole Kipke,Chunguang Chen,Robert Bozsak,Eyke Schöniger,Florian Ehehalt,Marius Distler,Ana Brennand,Stefan R. Bornstein,Jürgen Weitz,Michele Solimena,Stephan Speier +14 more
TL;DR: It is shown that, in tissue of pre-diabetic, impaired glucose-tolerant subjects, β cell volume is unchanged, but function significantly deteriorates, exhibiting increased basal release and loss of first-phase insulin secretion, and in individuals with type 2 diabetes, function within the sustainedβ cell volume further declines.