R
Robert H. Cleveland
Researcher at Boston Children's Hospital
Publications - 102
Citations - 3201
Robert H. Cleveland is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Chest radiograph & Pneumonia. The author has an hindex of 27, co-authored 102 publications receiving 2975 citations. Previous affiliations of Robert H. Cleveland include Harvard University & Icahn School of Medicine at Mount Sinai.
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Journal ArticleDOI
Enzyme-replacement therapy in life-threatening hypophosphatasia.
Michael P. Whyte,Cheryl R. Greenberg,Nada J. Salman,Michael B. Bober,William H. McAlister,Deborah Wenkert,Bradley J. Van Sickle,Jill H. Simmons,Terence S. Edgar,Martin L. Bauer,Mohamed A. Hamdan,Nick Bishop,Richard Lutz,Mairead McGinn,Stanley Craig,Jean N. Moore,John W. Taylor,Robert H. Cleveland,William R. Cranley,Ruth P. Lim,Tom D. Thacher,J. Mayhew,Matthew Downs,José Luis Millán,Alison Skrinar,Philippe Crine,Hal Landy +26 more
TL;DR: ENB-0040, an enzyme-replacement therapy, was associated with improved findings on skeletal radiographs and improved pulmonary and physical function in infants and young children with life-threatening hypophosphatasia.
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Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome
Leslie B. Gordon,Monica E. Kleinman,David T. Miller,Donna Neuberg,Anita Giobbie-Hurder,Marie Gerhard-Herman,Leslie B. Smoot,Catherine M. Gordon,Robert H. Cleveland,Brian D. Snyder,Brian Fligor,W. Robert Bishop,Paul Statkevich,Amy Regen,Andrew L. Sonis,Susan Riley,Christine Ploski,Annette Correia,Nicolle Quinn,Nicole J. Ullrich,Ara Nazarian,Marilyn G. Liang,Susanna Y. Huh,Armin Schwartzman,Mark W. Kieran,Mark W. Kieran +25 more
TL;DR: Results from this clinical treatment trial for children with HGPS provide preliminary evidence that lonafarnib may improve vascular stiffness, bone structure, and audiological status.
Journal ArticleDOI
Multidetector CT Evaluation of Congenital Lung Anomalies
TL;DR: Important clinical aspects, characteristic imaging features, and key points that allow differentiation among various anomalies are highlighted for a variety of common and uncommon conditions.
Journal ArticleDOI
Necrotising pneumonia is an increasingly detected complication of pneumonia in children
TL;DR: Despite the serious morbidity, massive parenchymal damage and prolonged hospitalisations, long-term outcome following necrotising pneumonia is excellent and the age range of cases has broadened.
Journal ArticleDOI
Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome
Leslie B. Gordon,Monica E. Kleinman,Joseph M. Massaro,Ralph B. D'Agostino,Heather Shappell,Marie Gerhard-Herman,Leslie B. Smoot,Catherine M. Gordon,Robert H. Cleveland,Ara Nazarian,Brian D. Snyder,Nicole J. Ullrich,V. Michelle Silvera,Marilyn G. Liang,Nicolle Quinn,David T. Miller,Susanna Y. Huh,Anne A. Dowton,Kelly Littlefield,Maya Mundkur Greer,Mark W. Kieran +20 more
TL;DR: Comparisons with lonafarnib monotherapy treatment reveal additional bone mineral density benefit but likely no added cardiovascular benefit with the addition of pravastatin and zoledronic acid.