R
Robert John Ardecky
Researcher at DuPont
Publications - 6
Citations - 901
Robert John Ardecky is an academic researcher from DuPont. The author has contributed to research in topics: Angiotensin II & Angiotensin receptor. The author has an hindex of 4, co-authored 6 publications receiving 895 citations.
Papers
More filters
Journal ArticleDOI
Identification of angiotensin II receptor subtypes
Andrew T. Chiu,William F. Herblin,Dale E. McCall,Robert John Ardecky,David J. Carini,John V. Duncia,Lori J. Pease,Pancras C. Wong,Ruth R. Wexler,Alexander L. Johnson,Pieter B.M.W.M. Timmermans +10 more
TL;DR: Two distinct subtypes of the angiotensin II receptor in the rat adrenal gland are demonstrated using radioligand binding and tissue section autoradiography and the discovery of two structurally dissimilar, nonpeptide compounds that show reciprocal selectivity for the two subtypes.
Patent
Fused-ring aryl substituted imidazoles
TL;DR: Substituted imidazoles of formula (I) are useful as angiotensin II blockers as discussed by the authors, these compounds have activity in treating hypertension and congestive heart failure.
Patent
Bis-naphthalimides as anticancer agents
TL;DR: In this article, the authors provided novel bis-napthalimide compounds useful as antitumor agents, pharmaceutical compositions containing them and processes for preparing intermediates to such compounds.
Patent
Treatment of CNS disorders with 4,5,6,7-tetrahydro-1H-imidazo (4,5-)-pyridines and analogs
TL;DR: In this article, 4,5,6,7-tetrahydro-1H-imidazo(4,5-c)-pyridine derivatives, methods for preparing them, pharmaceutical compositions containing them, and methods of using them to treat disorders of mammals mediated by AII type-2 receptors in the central nervous system.
Patent
Substituted imidazoles useful as angiotensin ii blockers
TL;DR: Substituted imidazoles (1) are useful as angiotensin II blockers and have been shown to have activity in treating hypertension and congestive heart failure as mentioned in this paper.