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Showing papers by "Roberto Kolter published in 1982"


Journal ArticleDOI
TL;DR: This paper presents a meta-anatomical model of the structure of the leader Peptide molecule and discusses its role in the development of inhibitory signalling mechanisms.
Abstract: INTRODUCTION 1 13 PHYSIOLOGICAL EFFECTS OF AMINO ACID STARVATION 1 14 MODEL OF ATTENUATION IN AMINO ACID BIOSYNTHETIC OPERONS 1 14 STRUCTURE OF LEADER TRANSCRIPTS 1 16 BIOCHEMICAL STUDIES ON ATTENUATION 1 1 8 MUTATIONAL IDENTIFICATION O F FUNCTIONALLY IMPORTANT SEGMENTS OF THE LEADER TRANSCRIPT 120 Mutants Defective in Synthesis of the Leader Peptide .. ...... ....... .... ... ...... ...... 1 2 1 Mutations in the Coding Region for the Leader Peptide . 121 Mutations Aff ecting RNA Stem-Loop Structures 123 OTHER FEATURES OF ATTENUATION 126 ATTENUATION IS AN ECONOMICAL CONTROL PROCESS 128 OTHER EXAMPLES OF ATTENUATION 129

195 citations


Journal ArticleDOI
TL;DR: It can be concluded that the π structural gene encodes for a protein of a molecular weight of approximately 35,000 that is the only protein containing more than 50 amino acid residues that is encoded by this 1583 base-pair replicon.

120 citations


Journal ArticleDOI
TL;DR: The role of π in regulating the initiation of R6K DNA replication and in regulating its own expression was investigated in this paper, where the π protein was found to reduce β-galactosidase expression from the lacZ gene fused to the pir promoter.

75 citations


Journal ArticleDOI
TL;DR: A contiguous region of DNA, 240 base-pairs in length, was identified as the functional γ origin of replication on the basis that Tn5 insertions within this region inactivated the origin.

55 citations