R
Roberto Lent
Researcher at Federal University of Rio de Janeiro
Publications - 96
Citations - 6015
Roberto Lent is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Corpus callosum & Cerebral cortex. The author has an hindex of 31, co-authored 91 publications receiving 5313 citations. Previous affiliations of Roberto Lent include Massachusetts Institute of Technology.
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Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled‐up primate brain
Frederico A. C. Azevedo,Ludmila R.B. Carvalho,Lea T. Grinberg,José Marcelo Farfel,Renata E.L. Ferretti,Renata Elaine Paraizo Leite,Wilson Jacob Filho,Roberto Lent,Suzana Herculano-Houzel +8 more
TL;DR: The findings challenge the common view that humans stand out from other primates in their brain composition and indicate that, with regard to numbers of neuronal and nonneuronal cells, the human brain is an isometrically scaled‐up primate brain.
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Isotropic Fractionator: A Simple, Rapid Method for the Quantification of Total Cell and Neuron Numbers in the Brain
TL;DR: A novel, fast, and inexpensive method to quantify total numbers of neuronal and non-neuronal cells in the brain or any dissectable regions thereof, which consists of transforming highly anisotropic brain structures into homogeneous, isotropic suspensions of cell nuclei, which can be counted and identified immunocytochemically as neuronal or non-NEuronal.
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Cellular scaling rules for rodent brains
TL;DR: It is proposed that the faster increase in average neuronal size in the cerebral cortex than in the cerebellum as these structures gain neurons and the rapidly increasing glial numbers that generate glial mass to match total neuronal mass at a fixed glia/neuron total mass ratio are fundamental cellular constraints that lead to the relative expansion of cerebral cortical volume across species.
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Changing numbers of neuronal and non-neuronal cells underlie postnatal brain growth in the rat.
TL;DR: Postnatal rat brain development is characterized by dramatic changes in the cellular composition of the brain, whose growth is governed by different combinations of cell addition and loss, and changes in average cell size during the first months after birth.