R
Roberto Rittner
Researcher at State University of Campinas
Publications - 229
Citations - 2639
Roberto Rittner is an academic researcher from State University of Campinas. The author has contributed to research in topics: Conformational isomerism & Hydrogen bond. The author has an hindex of 25, co-authored 228 publications receiving 2492 citations. Previous affiliations of Roberto Rittner include Pontifical Catholic University of Rio de Janeiro & University of Liverpool.
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The role of hyperconjugation in the conformational analysis of methylcyclohexane and methylheterocyclohexanes
TL;DR: It is shown that, besides the steric repulsion model, the conformational energies of the compounds studied are dictated by hyperconjugative interactions involving mainly the methine hydrogen.
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EGFR Tyrosine Kinase Inhibitor (PD153035) Improves Glucose Tolerance and Insulin Action in High-Fat Diet–Fed Mice
Patrícia O. Prada,Eduardo R. Ropelle,Rosa H. Mourão,Cláudio T. De Souza,José Rodrigo Pauli,Dennys E. Cintra,André Almeida Schenka,Silvana A. Rocco,Roberto Rittner,Kleber G. Franchini,José Vassallo,Licio A. Velloso,José B.C. Carvalheira,Mario J.A. Saad +13 more
TL;DR: In vivo efficacy and associated molecular mechanisms by which PD153035, an EGFR tyrosine kinase inhibitor, improved diabetes control and insulin action and reduces subclinical inflammation in HFD-fed mice are investigated.
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Axial/equatorial proportions for 2-substituted cyclohexanones
TL;DR: The conformational preference of cycloheranones in chloroform has been measured using the Eliel method as discussed by the authors. But the conformational proportions were not accurate to within 10% for MeSe and MeSe.
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DNA Nucleobase Synthesis at Titan Atmosphere Analog by Soft X-rays †
TL;DR: Previous results showed that the organic chemistry on the Titan surface can be very complex and extremely rich in prebiotic compounds, so this work confirms that molecules like these on the early Earth have found a place to allow life to flourish.
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The F⋯HO intramolecular hydrogen bond forming five-membered rings hardly appear in monocyclic organofluorine compounds
TL;DR: In this article, it was shown that the geometric restrictions imposed by the rigid rings are the main reasons in preventing fluorine atoms from participating in such an intramolecular H-bond.