R
Roberto Sala
Researcher at University of Parma
Publications - 63
Citations - 3120
Roberto Sala is an academic researcher from University of Parma. The author has contributed to research in topics: Arginine & Arginine transport. The author has an hindex of 26, co-authored 60 publications receiving 2906 citations. Previous affiliations of Roberto Sala include French Institute of Health and Medical Research & University of Milan.
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Journal ArticleDOI
Acute Myocardial Infarction in Humans is Associated with Activation of Programmed Myocyte Cell Death in the Surviving Portion of the Heart
Giorgio Olivetti,Federico Quaini,Roberto Sala,Costanza Lagrasta,Domenico Corradi,Edgardo Bonacina,Steven R. Gambert,Elena Cigola,Piero Anversa +8 more
TL;DR: Apoptosis appears to be a significant complicating factor of acute myocardial infarction increasing the magnitude of myocyte cell death associated with coronary artery occlusion.
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Overexpression of fibronectin induced by diabetes or high glucose: phenomenon with a memory.
TL;DR: In this paper, the authors examined whether diabetes or high glucose induces changes in gene expression and whether such changes outlast the presence of metabolic abnormalities, and found that fibronectin mRNA levels were increased to 304 +/- 295% of control (mean +/- SD) in the kidney cortex (P less than 0.02).
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Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation
Nicola Giuliani,Simona Colla,Simona Colla,Francesca Morandi,Francesca Morandi,Mirca Lazzaretti,Mirca Lazzaretti,Roberto Sala,Roberto Sala,Sabrina Bonomini,Sabrina Bonomini,Maria Grano,Maria Grano,Silvia Colucci,Silvia Colucci,Mirija Svaldi,Mirija Svaldi,Vittorio Rizzoli,Vittorio Rizzoli +18 more
TL;DR: It is found that human myeloma cells suppress the formation of human osteoblast progenitors in bone marrow (BM) cultures and the potential contribution of interleukin-7 (IL-7) in the inhibitory effect on osteooblast formation and RUNX2/CBFA1 activity by human myELoma cells in coculture is shown.
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Human myeloma cells stimulate the receptor activator of nuclear factor-κB ligand (RANKL) in T lymphocytes: a potential role in multiple myeloma bone disease
Nicola Giuliani,Nicola Giuliani,Simona Colla,Roberto Sala,Roberto Sala,Matteo Moroni,Matteo Moroni,Mirca Lazzaretti,Mirca Lazzaretti,Silvia La Monica,Silvia La Monica,Sabrina Bonomini,Sabrina Bonomini,Magda Hojden,Magda Hojden,Gabriella Sammarelli,Gabriella Sammarelli,Sophie Barillé,Sophie Barillé,Régis Bataille,Régis Bataille,Vittorio Rizzoli,Vittorio Rizzoli +22 more
TL;DR: Osteoclastogenesis was stimulated by conditioned medium of T cells cocultured with HMCLs and inhibited by recombinant human osteoprotegerin (OPG; 100 ng/mL to 1 microg/mL).
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In human endothelial cells rapamycin causes mTORC2 inhibition and impairs cell viability and function.
Amelia Barilli,Rossana Visigalli,Roberto Sala,Gian C. Gazzola,Alessandro Parolari,Elena Tremoli,Sabrina Bonomini,Alexandra Simon,Ellen I. Closs,Valeria Dall'Asta,Ovidio Bussolati +10 more
TL;DR: A prolonged treatment with rapamycin impairs endothelial function and hinders cell viability, and endothelial damage seems dependent on mTORC2 inhibition.