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Showing papers by "Rodrigo Dienstmann published in 2019"


Journal ArticleDOI
TL;DR: Multivariable models suggest that the prognostic value of MSI and CMS groups is largely explained by CytoLym and CAF infiltration patterns, which confirm that tumor microenvironment infiltration patterns represent potent determinants of the risk for distant dissemination in early-stage CRC.

124 citations


Journal ArticleDOI
TL;DR: The main challenges and opportunities that these new trial designs may provide for a more efficient drug development process, which may ultimately help ensure that PCM becomes a reality for patients are described.

80 citations