Rolf Dario Frank

TL;DR: Data demonstrate that hematopoietic cells are the major pathologic site of TF expression during endotoxemia and suggest that multiple protease-activated receptors mediate crosstalk between coagulation and inflammation.

TL;DR: Egr-1 does contribute to the sustained expression of inflammatory mediators and to the maximal expression of TF at 8 hours in the kidneys and lungs, and these data indicate that Egr- 1 does not contribute toThe early inflammatory response in the kidney and lungs or the early systemicinflammatory response in endotoxemic mice.

TL;DR: The data suggest that fondaparinux reduces kidney I/R injury primarily by inhibiting the recruitment of neutrophils, a synthetic pentasaccharide that selectively inhibits factor Xa in the coagulation cascade.

TL;DR: The findings indicate that the anti-inflammatory activity of fondaparinux can be dissociated from its anticoagulant activity and that NAC-pentasaccharide is protective in kidney I/R injury.

TL;DR: Effect of intravenous high-dose methylprednisolone on coagulation and fibrinolysis markers -