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Rolf Karlsten

Researcher at Uppsala University

Publications -  49
Citations -  2167

Rolf Karlsten is an academic researcher from Uppsala University. The author has contributed to research in topics: Neuropathic pain & Chronic pain. The author has an hindex of 23, co-authored 45 publications receiving 1964 citations. Previous affiliations of Rolf Karlsten include Uppsala University Hospital.

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Mechanical Chest Compressions and Simultaneous Defibrillation vs Conventional Cardiopulmonary Resuscitation in Out-of-Hospital Cardiac Arrest: The LINC Randomized Trial

TL;DR: There was no significant difference in 4-hour survival between patients treated with the mechanical CPR algorithm or those treated with guideline-adherent manual CPR, and the vast majority of survivors in both groups had good neurological outcomes by 6 months.
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Increased cortical cerebral blood flow with LUCAS; a new device for mechanical chest compressions compared to standard external compressions during experimental cardiopulmonary resuscitation.

TL;DR: Chest compressions with the LUCAS device during experimental cardiopulmonary resuscitation resulted in higher cerebral blood flow and cardiac output than standard manual external chest compressions, which strongly support prospective randomised studies in patients to evaluate this new device.
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The incidence of chronic post-sternotomy pain after cardiac surgery : a prospective study

TL;DR: The aim of this study was to determine the incidence of chronic post‐sternotomy pain in patients undergoing sternotomy for cardiac surgery in general and according to the specific surgical procedure.
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The analgesic effect of intravenous ketamine and lidocaine on pain after spinal cord injury.

TL;DR: The analgesic effect of ketamine and lidocaine was examined in a group of patients with neuropathic pain below the level of spinal cord injury and sensory abnormalities were assessed to see if this could help to identify responders and if treatments resulted in changes of sensibility.
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Central nervous system effects of subdissociative doses of (S)-ketamine are related to plasma and brain concentrations measured with positron emission tomography in healthy volunteers.

TL;DR: Memory impairment and psychotomimetic effects were related to dose, plasma concentration 4 minutes after administration, and decreased regional binding of (S)‐ketamine in the brain and were consistently seen at plasma and maximum regional brain (S)]ketamine concentrations higher than 70 and 500 ng/ml, respectively.