P
Per Hartvig
Researcher at University of Copenhagen
Publications - 215
Citations - 8175
Per Hartvig is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Dopaminergic & Positron emission tomography. The author has an hindex of 49, co-authored 215 publications receiving 7971 citations. Previous affiliations of Per Hartvig include Uppsala University & National Board of Health and Welfare.
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Journal ArticleDOI
Mapping human brain monoamine oxidase A and B with 11C-labeled suicide inactivators and PET.
Joanna S. Fowler,Robert R. MacGregor,Alfred P. Wolf,Carroll D. Arnett,Stephen L. Dewey,David J. Schlyer,David R. Christman,Jean Logan,Maynard E. Smith,H. Sachs,Sten-Magnus Aquilonius,Peter Bjurling,Christer Halldin,Per Hartvig,Klaus L. Leenders,Hans Lundqvist,Lars Oreland,C.-G. Stålnacke,Bengt Långström +18 more
TL;DR: Suicide enzyme inactivators labeled with positron emitters can be used to quantitate the distribution and kinetic characteristics of MAO in human brain structures and show rapid clearance of the inactive enantiomer and retention of the active enantiomers within MAO B-rich brain structures.
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Nerve growth factor affects 11C-nicotine binding, blood flow, EEG, and verbal episodic memory in an Alzheimer patient (case report).
Lars Olson,Agneta Nordberg,H. von Holst,Lars Bäckman,Ted Ebendal,Irina Alafuzoff,Kaarina Amberla,Per Hartvig,Agneta Herlitz,Anders Lilja,Hans Lundqvist,Bengt Långström,Björn A. Meyerson,Anders Persson,Matti Viitanen,Bengt Winblad,Åke Seiger +16 more
TL;DR: It is indicated that NGF may counteract cholinergic deficits in AD, and it is suggested that further clinical trials of NGF infusion in AD are warranted.
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Increased dopamine synthesis rate in medial prefrontal cortex and striatum in schizophrenia indicated by L-(β-11C) DOPA and PET
Leif Lindström,O. Gefvert,Gisela E. Hagberg,T. Lundberg,Mats Bergström,Per Hartvig,Bengt Långström +6 more
TL;DR: The results indicate that the synthesis of dopamine is elevated within the striatum and parts of medial prefrontal cortex in schizophrenia.
Journal ArticleDOI
Patient-controlled Analgesic Therapy, Part IV: Pharmacokinetics and Analgesic Plasma Concentrations of Morphine
TL;DR: The pharmacokinetics of ketobemidone were not influenced by the addition of a spasmolytic agent in the commercial combination ketobamidone preparation ‘Ketogin’ and did not differ significantly in these respects.
Journal ArticleDOI
Kinetic analysis of regional (S)(-)11C-nicotine binding in normal and Alzheimer brains--in vivo assessment using positron emission tomography.
TL;DR: The described kinetic model allowed in vivo quantification of nicotinic receptor binding in brain, which will be of importance in the future for evaluation of diagnosis, progress of disease, as well as the therapeutic effects in the treatment of AD.