R
Rolf Lood
Researcher at Lund University
Publications - 44
Citations - 1146
Rolf Lood is an academic researcher from Lund University. The author has contributed to research in topics: Propionibacterium acnes & Bacteriophage. The author has an hindex of 14, co-authored 40 publications receiving 833 citations. Previous affiliations of Rolf Lood include Rockefeller University.
Papers
More filters
Journal ArticleDOI
Biofilm formation by Propionibacterium acnes is a characteristic of invasive isolates
Anna Holmberg,Rolf Lood,Matthias Mörgelin,Bo Söderquist,Elisabet Holst,Mattias Collin,Bertil Christensson,Magnus Rasmussen +7 more
TL;DR: The presence of human plasma in solution or at the plastic surface inhibits biofilm formation, which could explain why P. acnes primarily infect plasma-poor environments of, for example, joint prostheses and cerebrospinal shunts.
Journal ArticleDOI
Novel Phage Lysin Capable of Killing the Multidrug-Resistant Gram-Negative Bacterium Acinetobacter baumannii in a Mouse Bacteremia Model
Rolf Lood,Benjamin Y. Winer,Adam J. Pelzek,Roberto Díez-Martínez,Mya Thandar,Chad W. Euler,Raymond Schuch,Vincent A. Fischetti +7 more
TL;DR: PlyF307 represents the first highly active therapeutic lysin specific for Gram-negative organisms in an array of native lysins found in Acinetobacter phage and rescued mice from lethal A. baumannii bacteremia.
Journal ArticleDOI
Novel Engineered Peptides of a Phage Lysin as Effective Antimicrobials against Multidrug-Resistant Acinetobacter baumannii.
Mya Thandar,Rolf Lood,Benjamin Y. Winer,Douglas R. Deutsch,Chad W. Euler,Vincent A. Fischetti +5 more
TL;DR: The prospect of using peptide derivatives from bacteriophage lysins to treat topical infections and remove biofilms caused by Gram-negative pathogens is demonstrated.
Journal ArticleDOI
Revisiting Antibiotic Resistance Spreading in Wastewater Treatment Plants - Bacteriophages as a Much Neglected Potential Transmission Vehicle.
TL;DR: Current literature in the role of WWTPs as reservoirs and hotspots of antibiotic resistance with a specific focus on bacteriophages as mediators of genetic exchange is examined, highlighting the importance of transduction in WWTBs as a mediator of resistance spread.
Journal ArticleDOI
IgG glycan hydrolysis by endoglycosidase S diminishes the proinflammatory properties of immune complexes from patients with systemic lupus erythematosus: A possible new treatment?
Christian Lood,Maria Allhorn,Rolf Lood,Birgitta Gullstrand,Anders I. Olin,Lars Rönnblom,Lennart Truedsson,Mattias Collin,Anders A. Bengtsson +8 more
TL;DR: Findings indicate that endoglycosidase S treatment has prominent effects on several pathogenetically important IC-mediated events, and suggest that EndoS has the potential to be developed as a novel therapy for SLE.