Ronald G. Manning

TL;DR: Local cerebral uptake of deoxyglucose labeled with fluorine 18 was measured by positron-emission tomography in eight patients with schizophrenia and in six age-matched normal volunteers, indicating relatively lower glucose use than normal control subjects.

TL;DR: The results indicate that brain oxidative metabolism, when measured under resting conditions with reduced sensory input, is not reduced in relation to age in healthy men and no significant relations between intelligence and resting cerebral metabolism are evident.

TL;DR: The results indicate that the cerebral metabolic rate for glucose is not correlated with age in healthy men.

TL;DR: Positron emission tomography with simultaneous electroencephalographic monitoring was performed with {18F}fluorodeoxyglucose in 20 patients with complex partial seizures who had normal computed tomographic scans, finding a tendency for patients to have higher overall metabolic rates when taking less medication.

TL;DR: The development of the 18F-labeled 2-fluorodeoxyglucose (218FDG) method has produced a powerful tool for studying cerebral energy metabolism with positron tomography in resting subjects and schizophrenic subjects at rest and off medication.