R
Ronald J. Doyle
Researcher at University of Louisville
Publications - 147
Citations - 5691
Ronald J. Doyle is an academic researcher from University of Louisville. The author has contributed to research in topics: Bacillus subtilis & Cell wall. The author has an hindex of 40, co-authored 147 publications receiving 5555 citations.
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Microbial cell surface hydrophobicity
Ronald J. Doyle,Mel Rosenberg +1 more
TL;DR: The importance of hydrophobicity in the adhesiveness of pathogenic Gram-negative bacteria, especially Candida species, and the importance of surface free energy as a hydphobicity measure in bacterial adhesion to solid surfaces is studied.
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The energized membrane and cellular autolysis in Bacillus subtilis
TL;DR: The results suggest that cellular lysis in B. subtilis and energized membrane are tightly coupled, which is interpreted to suggest that the in vivo control of autolysin activity is related to the energized membranes.
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Contribution of the hydrophobic effect to microbial infection.
TL;DR: The literature provides compelling evidence that a large number of bacterial and fungal pathogens depend on hydrophobic interactions for successful colonization of a host and several laboratories are now developing effective antiadhesins, based on inhibition of hydrophilic interactions between the host and the pathogen.
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Chemical basis for selectivity of metal ions by the Bacillus subtilis cell wall.
TL;DR: Hill plots of equilibrium dialysis data suggest that metal binding to cell walls involves negative cooperativity, and competition between various metals for binding sites suggested that the cations complex with identical sites on the cell walls.
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On the origin of membrane vesicles in Gram-negative bacteria
TL;DR: It is proposed that the genesis of extracellular membrane vesicles in Gram-negative bacteria is a result of cell wall turnover, and peptidoglycan turnover would cause a turgor on the outer membranes, causing the outer membrane to bulge and finally bleb.