R
Ronald J. Patterson
Researcher at Michigan State University
Publications - 37
Citations - 2393
Ronald J. Patterson is an academic researcher from Michigan State University. The author has contributed to research in topics: RNA splicing & Galectin. The author has an hindex of 19, co-authored 36 publications receiving 2257 citations.
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Journal ArticleDOI
Intracellular functions of galectins
TL;DR: This review summarizes the intracellular activities displayed by several galectins and discusses the possible underlying mechanisms.
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Identification of galectin-3 as a factor in pre-mRNA splicing
TL;DR: A requirement for galectin-3 in pre-mRNA splicing is defined and the addition of other lectins, either with a similar saccharide binding specificity or with a different specificity, did not restore splicing activity.
Journal ArticleDOI
Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein
TL;DR: Results provide strong evidence that galectin-1 and galECTin-3, by interacting with Gemin4, play a role in spliceosome assembly in vivo.
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Evidence for a role for galectin-1 in pre-mRNA splicing.
TL;DR: Nuclear galectins exhibit functional redundancy in their splicing activity and partition, at least partially, in the nucleoplasm with another known splicing factor.
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Dynamics of galectin-3 in the nucleus and cytoplasm.
Kevin C. Haudek,Kimberly J. Spronk,Patricia G. Voss,Ronald J. Patterson,John L. Wang,Eric J. Arnoys +5 more
TL;DR: This review summarizes selected studies on galectin-3 (Gal3) as an example of the dynamic behavior of a carbohydrate-binding protein in the cytoplasm and nucleus of cells and investigates the significance of the protein's carbohydrate- binding activity.