R
Ronald N. Zuckermann
Researcher at Lawrence Berkeley National Laboratory
Publications - 240
Citations - 16517
Ronald N. Zuckermann is an academic researcher from Lawrence Berkeley National Laboratory. The author has contributed to research in topics: Peptoid & Side chain. The author has an hindex of 62, co-authored 233 publications receiving 15120 citations. Previous affiliations of Ronald N. Zuckermann include Chiron Corporation & Northwestern University.
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Efficient method for the preparation of peptoids [oligo(N-substituted glycines)] by submonomer solid-phase synthesis
TL;DR: In this article, the authors present an automated solid-phase method for the synthesis of oligo(N-substituted glycines) (NSGs) which is general for a wide variety of side-chain substituents and allows the rapid synthesis of molecules of potential therapeutic interest.
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Peptoids: a modular approach to drug discovery.
Reyna J. Simon,R S Kania,Ronald N. Zuckermann,Verena D. Huebner,David Jewell,Steven C. Banville,Simon Ng,L Wang,Steven Rosenberg,C K Marlowe +9 more
TL;DR: Peptoids, oligomers of N-substituted glycines, are described as a motif for the generation of chemically diverse libraries of novel molecules and peptide ligands of three biological systems were found with affinities comparable to those of the corresponding peptides.
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Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides
Nathaniel P. Chongsiriwatana,James A. Patch,Ann M. Czyzewski,Michelle T. Dohm,Andrey Ivankin,David Gidalevitz,Ronald N. Zuckermann,Annelise E. Barron +7 more
TL;DR: The in vitro activities of ampetoids are strikingly similar to those of AMPs themselves, suggesting a strong mechanistic analogy, and add to the growing evidence that nonnatural foldamers will emerge as an important class of therapeutics.
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Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library.
Ronald N. Zuckermann,Eric J. Martin,David C. Spellmeyer,G B Stauber,K R Shoemaker,Janice M. Kerr,G. M. Figliozzi,Dane Goff,Michael A. Siani,Reyna J. Simon +9 more
TL;DR: Screening a diverse, combinatorial library of ca.
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Gold nanoparticle self-similar chain structure organized by DNA origami.
TL;DR: It is shown for the first time that a large DNA complex and multiple AuNP conjugates can be well-assembled and purified with reliable yields and could be used to generate high local-field enhancement.