R
Ronald Schoenmakers
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 9
Citations - 831
Ronald Schoenmakers is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Transgene & Self-healing hydrogels. The author has an hindex of 8, co-authored 9 publications receiving 801 citations. Previous affiliations of Ronald Schoenmakers include University of Zurich.
Papers
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Journal ArticleDOI
Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: Systematic modulation of a synthetic cell-responsive PEG-hydrogel
Thomas P. Kraehenbuehl,Prisca Zammaretti,André J. van der Vlies,Ronald Schoenmakers,Matthias P. Lutolf,Marisa Jaconi,Jeffrey A. Hubbell +6 more
TL;DR: It is shown that synthetic three-dimensional matrix metalloproteinase (MMP)-sensitive poly(ethylene glycol) (PEG)-based hydrogels can direct differentiation of pluripotent cardioprogenitors, using P19 embryonal carcinoma (EC) cells as a model, along a cardiac lineage in vitro.
Journal ArticleDOI
Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions.
Martin Ehrbar,Simone C. Rizzi,Ronald Schoenmakers,Blanca San Miguel,Jeffrey A. Hubbell,Franz E. Weber,Matthias P. Lutolf +6 more
TL;DR: In this article, the design of oligopeptide building blocks with dual enzymatic responsiveness allows to create polymer networks that are formed and functionalized via enzymes and are degradable via other enzymes, both occurring under physiological conditions.
Patent
Biomaterials formed by nucleophilic addition reaction to conjugated unsaturated groups
Jeffrey A. Hubbell,Donald L. Elbert,Matthias P. Lutolf,Alison Pratt,Ronald Schoenmakers,Nicola Tirelli,Brent Vernon +6 more
TL;DR: This paper used nucleophilic addition reactions to conjugated unsaturated groups to create polymeric biomaterials formed by nucleophilicity of nucleophiles for medical treatments, which can be used for medical applications.
Patent
Conjugate addition reactions for the controlled delivery of pharmaceutical active compounds
TL;DR: This article used nucleophilic addition reactions to conjugated unsaturated groups to create polymeric biomaterials formed by nucleophilicity of nucleophiles for medical treatments, which can be used for medical applications.
Journal ArticleDOI
Engineered Streptomyces quorum-sensing components enable inducible siRNA-mediated translation control in mammalian cells and adjustable transcription control in mice.
Wilfried Weber,Laetitia Malphettes,Maria De Jesus,Ronald Schoenmakers,Marie Daoud El-Baba,Manuela Spielmann,Bettina G. Keller,Cornelia C. Weber,Petra van de Wetering,Dominique Aubel,Florian M. Wurm,Martin Fussenegger +11 more
TL;DR: Recent advances in functional genomics, gene therapy, tissue engineering, drug discovery and biopharmaceuticals production have been fostered by precise small‐molecule‐mediated fine‐tuning of desired transgenes.