R
Ronen Shemesh
Researcher at Compugen
Publications - 64
Citations - 2446
Ronen Shemesh is an academic researcher from Compugen. The author has contributed to research in topics: Receptor & G protein-coupled receptor. The author has an hindex of 17, co-authored 64 publications receiving 2328 citations.
Papers
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Journal ArticleDOI
Systematic identification of abundant A-to-I editing sites in the human transcriptome
Erez Y. Levanon,Erez Y. Levanon,Eli Eisenberg,Rodrigo Yelin,Sergey Nemzer,Martina Hallegger,Ronen Shemesh,Zipora Y. Fligelman,Avi Shoshan,Sarah Pollock,Dan Sztybel,Moshe Olshansky,Gideon Rechavi,Michael F. Jantsch +13 more
TL;DR: A computational search for ADAR editing sites in the human transcriptome is described, using millions of available expressed sequences and indicates the role of editing in controlling dsRNA stability.
Patent
Methods and systems for annotating biomolecular sequences
Alex Diber,Sarah Pollock,Zurit Levine,Sergey Nemzer,Vladimir Grebinsky,Brian Melon,Andrew Olson,Avi Rosenberg,Ami Haviv,Shaul Zevin,Tomer Zekharia,Zipi Shaked,Moshe Olshansky,Ariel Farkash,Eyal Privman,Amit Novik,Naomi Keren,Gad S. Cojocaru,Pinchas Akiva,Yossi Cohen,Ronen Shemesh,Osnat Sella-Tavor,Liat Mintz,Hanqing Xie,Dvir Dahary,Erez Y. Levanon,Shiri Freilich,Nili Beck,Wei-Yong Zhu,Alon Wasserman,Chen Chermesh,Idit Azar,Rotem Sorek,Jeanne Bernstein +33 more
TL;DR: Polypeptide sequences and polynucleotide sequences are provided in this paper, along with annotative information concerning such sequences and uses for these sequences and their sequences are annotated.
Journal ArticleDOI
Transcription-mediated gene fusion in the human genome
Pinchas Akiva,Amir Toporik,Sarit Edelheit,Yifat Peretz,Alex Diber,Ronen Shemesh,Amit Novik,Rotem Sorek +7 more
TL;DR: It is demonstrated that at least half of these fusions exist in human tissues, and it is shown that unique splicing patterns dominate the functional and regulatory nature of the resulting transcripts, and found intergenic distance bias in fused compared with nonfused genes.
Journal ArticleDOI
Evolutionarily conserved human targets of adenosine to inosine RNA editing
Erez Y. Levanon,Martina Hallegger,Yaron Kinar,Ronen Shemesh,Kristina Djinović-Carugo,Gideon Rechavi,Michael F. Jantsch,Eli Eisenberg,Eli Eisenberg +8 more
TL;DR: In this paper, the authors identified and experimentally verified four additional human substrates for ADAR-mediated editing: FLNA, BLCAP, CYFIP2 and IGFBP7.
Journal ArticleDOI
Evolutionarily conserved human targets of adenosine to inosine RNA editing
Erez Y. Levanon,Martina Hallegger,Yaron Kinar,Ronen Shemesh,Kristina Djinović-Carugo,Gideon Rechavi,Michael F. Jantsch,Eli Eisenberg,Eli Eisenberg +8 more
TL;DR: Four additional candidate human substrates for ADAR-mediated editing are identified and experimentally verified: FLNA, BLCAP, CYFIP2 and IGFBP7, none of these substrates encodes a receptor protein but two of them are strongly expressed in the CNS and seem important for proper nervous system function.