Rong-Xiu Zhu

TL;DR: A chemical investigation of the endolichenic fungus Aspergillus versicolor (125a), which was found in the lichen Lobaria quercizans, resulted in the isolation of four novel diphenyl ethers and fifteen known compounds, 15–29.

TL;DR: Six novel phototoxins, phaeosphaerins A-F, together with six known perylenequinones were isolated from an endolichenic fungus and their structures were determined unequivocally on the basis of comprehensive analysis of MS and NMR data as well as electronic circular dichroism calculations.

TL;DR: A polyamide column chromatography method using an aqueous ammonia mobile phase was developed for large-scale accumulation of water-soluble indoline amide glucosides from a medicinal plant, Portulaca oleracea.

TL;DR: Bioassay of the isolated compounds found that pyridoxatin was cytotoxic to human cancer cells by induction of G0/G1 cell cycle arrest and apoptosis, and structures of these compounds were determined by comprehensive analysis of spectroscopic data and single-crystal X-ray diffraction determination.

TL;DR: The most potent compound, compound 4, also sensitized clinically derived azole-resistant Candida albicans strains to fluconazole (FLC), and inhibited the function of efflux pumps and reduced the transcriptional expression of the efflux-pump-related genes CDR1 and CDR2.