R
Rosaria Maria Pipitone
Researcher at University of Palermo
Publications - 68
Citations - 3177
Rosaria Maria Pipitone is an academic researcher from University of Palermo. The author has contributed to research in topics: Fatty liver & Nonalcoholic fatty liver disease. The author has an hindex of 24, co-authored 59 publications receiving 2429 citations. Previous affiliations of Rosaria Maria Pipitone include University of Milan.
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Journal ArticleDOI
The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent
Rosellina Margherita Mancina,Paola Dongiovanni,Salvatore Petta,Piero Pingitore,Marica Meroni,R. Rametta,Jan Borén,Tiziana Montalcini,Arturo Pujia,Olov Wiklund,Olov Wiklund,George Hindy,Rocco Spagnuolo,Benedetta Maria Motta,Rosaria Maria Pipitone,Antonio Craxì,Silvia Fargion,Valerio Nobili,Pirjo Käkelä,Vesa Kärjä,Ville Männistö,Jussi Pihlajamäki,Dermot F. Reilly,Jose Castro-Perez,Jose Castro-Perez,Julia Kozlitina,Luca Valenti,Stefano Romeo,Stefano Romeo,Stefano Romeo +29 more
TL;DR: Evidence is provided for an association between the MBOAT7 rs641738 variant and the development and severity of NAFLD in individuals of European descent that seems to be mediated by changes in the hepatic phosphatidylinositol acyl-chain remodeling.
Journal ArticleDOI
Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease
Paola Dongiovanni,Salvatore Petta,Cristina Maglio,Anna Ludovica Fracanzani,Rosaria Maria Pipitone,Enrico Mozzi,Benedetta Maria Motta,Dorota Kaminska,Raffaela Rametta,Stefania Grimaudo,Serena Pelusi,Tiziana Montalcini,Anna Alisi,Marco Maggioni,Vesa Kärjä,Jan Borén,Pirjo Käkelä,Vito Di Marco,Chao Xing,Valerio Nobili,Bruno Dallapiccola,Antonio Craxì,Jussi Pihlajamäki,Silvia Fargion,Lars Sjöström,Lena M. S. Carlsson,Stefano Romeo,Luca Valenti +27 more
TL;DR: The findings suggest that reduced ability to export VLDLs is deleterious for the liver, and carriers of the TM6SF2 E167K variant are more susceptible to progressive NASH, but are protected against cardiovascular disease.
Journal ArticleDOI
Statin use and non-alcoholic steatohepatitis in at risk individuals
Paola Dongiovanni,Salvatore Petta,Ville Männistö,Rosellina Margherita Mancina,Rosaria Maria Pipitone,Vesa Kärjä,Marco Maggioni,Pirjo Käkelä,Olov Wiklund,Enrico Mozzi,Stefania Grimaudo,Dorota Kaminska,Raffaela Rametta,Antonio Craxì,Silvia Fargion,Valerio Nobili,Stefano Romeo,Stefano Romeo,Jussi Pihlajamäki,Luca Valenti +19 more
TL;DR: Statin use was associated with protection towards the full spectrum of liver damage in individuals at risk of non-alcoholic steatohepatitis, however, the I148M PNPLA3 risk variant limited this beneficial effect.
Journal ArticleDOI
Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver.
Paola Dongiovanni,Stefan Stender,Alessandro Pietrelli,Rosellina Margherita Mancina,A. Cespiati,Salvatore Petta,Serena Pelusi,Piero Pingitore,Sara Badiali,Marco Maggioni,Ville Männistö,Stefania Grimaudo,Rosaria Maria Pipitone,Jussi Pihlajamäki,Antonio Craxì,Magdalena Taube,Lena M. S. Carlsson,Silvia Fargion,Stefano Romeo,Stefano Romeo,Stefano Romeo,Julia Kozlitina,Luca Valenti +22 more
TL;DR: The aim of this study was to examine whether hepatic fat accumulation has a causal role in determining liver damage and insulin resistance.
Journal ArticleDOI
Effects of Eradicating Hepatitis C Virus Infection in Patients With Cirrhosis Differ With Stage of Portal Hypertension
Vito Di Marco,Vincenza Calvaruso,Donatella Ferraro,M.G. Bavetta,Giuseppe Cabibbo,Elisabetta Conte,Calogero Cammà,Stefania Grimaudo,Rosaria Maria Pipitone,F. Simone,S. Peralta,A. Arini,Antonio Craxì +12 more
TL;DR: In a prospective study of 444 patients with HCV and compensated cirrhosis, HCV eradication reduced risk for liver decompensation, HCC, and death, regardless of whether the patients had EVs.