R
Rosaria Meli
Researcher at University of Naples Federico II
Publications - 176
Citations - 9235
Rosaria Meli is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Palmitoylethanolamide & Oxidative stress. The author has an hindex of 46, co-authored 163 publications receiving 7852 citations. Previous affiliations of Rosaria Meli include Yale University.
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Journal ArticleDOI
Potential beneficial effects of butyrate in intestinal and extraintestinal diseases
Roberto Berni Canani,Margherita Di Costanzo,Ludovica Leone,Monica Pedata,Rosaria Meli,Antonio Calignano +5 more
TL;DR: A wide spectrum of positive effects exerted by butyrate is suggested, with a high potential for a therapeutic use in human medicine, at the extraintestinal and intestinal level.
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Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids in macrophage J774A.1.
TL;DR: It is suggested that inhibition of iNOS and COX-2 expression by flavonoids may be one of the mechanisms responsible for their anti-inflammatory effects.
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Rapid Broad-Spectrum Analgesia through Activation of Peroxisome Proliferator-Activated Receptor-alpha
Jesse LoVerme,Roberto Russo,Giovanna La Rana,Jin Fu,Jesse N. Farthing,Giuseppina Mattace-Raso,Rosaria Meli,Andrea G. Hohmann,Antonio Calignano,Daniele Piomelli +9 more
TL;DR: It is reported that agonists of the nuclear receptor PPAR-α (peroxisome proliferator-activated receptor-α) suppress pain behaviors induced in mice by chemical tissue injury, nerve damage, or inflammation and may represent a novel class of analgesics.
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Effects of Lactobacillus rhamnosus strain GG in pediatric obesity-related liver disease.
Pietro Vajro,Claudia Mandato,Maria Rosaria Licenziati,Adriana Franzese,Dino Franco Vitale,S. Lenta,M. Caropreso,Gianfranco Vallone,Rosaria Meli +8 more
TL;DR: Probiotic L rhamnosus strain GG warrants consideration as a therapeutic tool to treat hypertransaminasemia in hepatopathic obese children noncompliant with lifestyle interventions.
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Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy?
TL;DR: In this article, dual inhibitor compounds that will simultaneously inhibit COX and 5-LOX could enhance their individual anti-inflammatory effects and reduce the undesirable side effects associated with NSAIDs, especially of the gastrointestinal tract.