R
Roy Navon
Researcher at Agilent Technologies
Publications - 38
Citations - 4494
Roy Navon is an academic researcher from Agilent Technologies. The author has contributed to research in topics: Respiratory tract infections & Medicine. The author has an hindex of 14, co-authored 33 publications receiving 3864 citations. Previous affiliations of Roy Navon include Tel Aviv University & University of Parma.
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GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
Eran Eden,Roy Navon,Roy Navon,Israel Steinfeld,Israel Steinfeld,Doron Lipson,Zohar Yakhini,Zohar Yakhini +7 more
TL;DR: GOrilla is a web-based application that identifies enriched GO terms in ranked lists of genes, without requiring the user to provide explicit target and background sets, and its unique features and advantages over other threshold free enrichment tools include rigorous statistics, fast running time and an effective graphical representation.
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miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
Espen Enerly,Israel Steinfeld,Kristine Kleivi,Kristine Kleivi,Suvi-Katri Leivonen,Miriam Ragle Aure,Hege G. Russnes,Jo Anders Rønneberg,Jo Anders Rønneberg,Hilde Johnsen,Roy Navon,Einar Andreas Rødland,Rami Mäkelä,Bjørn Naume,Merja Perälä,Olli Kallioniemi,Olli Kallioniemi,Vessela N. Kristensen,Vessela N. Kristensen,Zohar Yakhini,Zohar Yakhini,Anne Lise Børresen-Dale,Anne Lise Børresen-Dale +22 more
TL;DR: This study presents and analyzes data derived from expression profiling of 799 miRNAs in 101 primary human breast tumors, along with genome-wide mRNA profiles and extensive clinical information, to identify statistical significant differential expression of mi RNAs between molecular intrinsic subtypes, and between samples with different levels of proliferation.
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Novel Rank-Based Statistical Methods Reveal MicroRNAs with Differential Expression in Multiple Cancer Types
Roy Navon,Hui Wang,Israel Steinfeld,Israel Steinfeld,Anya Tsalenko,Amir Ben-Dor,Zohar Yakhini +6 more
TL;DR: This study aims to identify miRNAs with consistent differential expression in multiple tumor types using a novel data analysis approach and develops scores for comparing miRNA expression in matched sample data based on a rigorous characterization of the distribution of order statistics over a discrete state set.
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A Novel Host-Proteome Signature for Distinguishing between Acute Bacterial and Viral Infections
Kfir Oved,Asi Cohen,Olga Boico,Roy Navon,Tom Friedman,Liat Etshtein,Or Kriger,Ellen Bamberger,Yura Fonar,Renata Yacobov,Ron Wolchinsky,Galit Denkberg,Yaniv Dotan,Amit Hochberg,Yoram Reiter,Moti Grupper,Isaac Srugo,Paul D. Feigin,Malka Gorfine,Irina Chistyakov,Ron Dagan,Adi Klein,Israel Potasman,Eran Eden +23 more
TL;DR: The accurate differential diagnosis provided by this novel combination of viral- and bacterial-induced proteins has the potential to improve management of patients with acute infections and reduce antibiotic misuse.
Journal ArticleDOI
Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor.
Liron Zehavi,Roi Avraham,Aviv Barzilai,Dalia Bar-Ilan,Roy Navon,Yechezkel Sidi,Yechezkel Sidi,Dror Avni,Raya Leibowitz-Amit +8 more
TL;DR: It is shown that the expression of miRNAs from a large cluster on human chromosome 14q32 is significantly down-regulated in melanoma cell lines, benign nevi and melanoma samples relative to normal melanocytes, and this work is the first to show that the large miRNA cluster on chromosome 14Q32 is silenced in melanomas.