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Bjørn Naume
Researcher at Oslo University Hospital
Publications - 155
Citations - 10225
Bjørn Naume is an academic researcher from Oslo University Hospital. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 46, co-authored 144 publications receiving 9006 citations. Previous affiliations of Bjørn Naume include Rikshospitalet–Radiumhospitalet & University of Oslo.
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Journal ArticleDOI
A pooled analysis of bone marrow micrometastasis in breast cancer
Stephan Braun,Florian D. Vogl,Bjørn Naume,Wolfgang Janni,Michael P. Osborne,R. Charles Coombes,Günter Schlimok,Ingo J. Diel,Bernd Gerber,Gerhard Gebauer,Jean-Yves Pierga,Christian Marth,Daniel Oruzio,Gro Wiedswang,E. F. Solomayer,Günther Kundt,B. Strobl,Tanja Fehm,George Y. Wong,Judith M Bliss,Anne Vincent-Salomon,Klaus Pantel +21 more
TL;DR: The presence of micrometastasis in the bone marrow at the time of diagnosis of breast cancer is associated with a poor prognosis.
Journal ArticleDOI
Allele-specific copy number analysis of tumors
Peter Van Loo,Silje H. Nordgard,Silje H. Nordgard,Ole Christian Lingjærde,Hege G. Russnes,Inga H. Rye,Wei Sun,Victor J. Weigman,Peter Marynen,Anders Zetterberg,Bjørn Naume,Charles M. Perou,Anne Lise Børresen-Dale,Vessela N. Kristensen +13 more
TL;DR: A genome-wide map of allelic skewness in breast cancer is constructed, indicating loci where one allele is preferentially lost, whereas the other allele isPreferentially gained, and it is hypothesized that these alternative alleles have a different influence on breast carcinoma development.
Journal ArticleDOI
Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms
Therese Sørlie,Yulei Wang,Chunlin Xiao,Hilde Johnsen,Bjørn Naume,Raymond R. Samaha,Anne Lise Børresen-Dale,Anne Lise Børresen-Dale +7 more
TL;DR: The results provide further evidence that these breast tumor subtypes represent biologically distinct disease entities and may require different therapeutic strategies, and validate by multiple gene expression platforms, the set of 54 predictor genes identified in this study.
Journal ArticleDOI
Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome
Anna Bergamaschi,Elda Tagliabue,Therese Sørlie,Therese Sørlie,Bjørn Naume,Tiziana Triulzi,Rosaria Orlandi,Hege G. Russnes,J. M. Nesland,Raija Tammi,Päivi Auvinen,Veli-Matti Kosma,Sylvie Ménard,Anne Lise Børresen-Dale,Anne Lise Børresen-Dale +14 more
TL;DR: It is suggested that primary breast tumours can be classified on the basis of the expression of extracellular matrix (ECM) composition and that this classification provides relevant information on the biology of breast carcinomas, further supporting the hypothesis that clinical outcome is strongly related to stromal characteristics.
Journal ArticleDOI
Novel patterns of genome rearrangement and their association with survival in breast cancer
James W. Hicks,Alexander Krasnitz,B. Lakshmi,Nicholas Navin,Michael Riggs,Evan Leibu,Diane Esposito,Joan Alexander,Jen Troge,Vladimir Grubor,Seungtai Yoon,Michael Wigler,Kenny Ye,Anne Lise Børresen-Dale,Bjørn Naume,Ellen Schlicting,Larry Norton,Torsten Hägerström,Lambert Skoog,Gert Auer,Susanne Månér,Pär Lundin,Anders Zetterberg +22 more
TL;DR: Analysis of a selected subset of clinical material suggests that a simple genomic calculation, based on the number and proximity of genomic alterations, correlates with life-table estimates of the probability of overall survival in patients with primary breast cancer.