R
Rozenn Le Berre
Researcher at French Institute of Health and Medical Research
Publications - 23
Citations - 1467
Rozenn Le Berre is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Pseudomonas aeruginosa & Lung injury. The author has an hindex of 14, co-authored 23 publications receiving 492 citations. Previous affiliations of Rozenn Le Berre include Lille University of Science and Technology.
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Journal ArticleDOI
Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis
Laurent Meijer,Deborah J. Nelson,Vladimir Riazanski,Aida G. Gabdoulkhakova,Geneviève Héry-Arnaud,Rozenn Le Berre,Nadège Loaëc,Nassima Oumata,Hervé Galons,Emmanuel Nowak,L. Guéganton,Guillaume Dorothée,Michaela Prochazkova,Bradford Hall,Ashok B. Kulkarni,Robert D. Gray,Adriano G. Rossi,Véronique Witko-Sarsat,Caroline Norez,Frédéric Becq,Denis Ravel,Dominique Mottier,Gilles Rault +22 more
TL;DR: The fact that (R)-roscovitine has undergone extensive preclinical safety/pharmacology studies, and phase I and II clinical trials in cancer patients, encourages its repurposing as a CF drug candidate.
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Relative contribution of three main virulence factors in Pseudomonas aeruginosa pneumonia.
Rozenn Le Berre,S. Nguyen,Emmanuel Nowak,Eric Kipnis,Maud Pierre,Lauriane E. Quenee,Florence Ader,Steve Lancel,René Courcol,Benoit Guery,Karine Faure +10 more
TL;DR: In a murine model of pneumonia, the data suggest that type 3 secretion system and elastase are the most important virulence factors in clinically relevant P. aeruginosa strains.
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Comparison of 2002 AECG and 2016 ACR/EULAR classification criteria and added value of salivary gland ultrasonography in a patient cohort with suspected primary Sjögren's syndrome.
Maëlle Le Goff,Divi Cornec,Sandrine Jousse-Joulin,Dewi Guellec,Sebastian Costa,Thierry Marhadour,Rozenn Le Berre,Steeve Genestet,Béatrice Cochener,Sylvie Boisramé-Gastrin,Yves Renaudineau,Jacques-Olivier Pers,Alain Saraux,Valérie Devauchelle-Pensec +13 more
TL;DR: Agreement between AECG and ACR/EULAR criteria sets is excellent and classified some patients without sicca symptoms as having pSS, which is slightly more sensitive than other classification criteria.
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Autosomic dominant familial Behçet disease and haploinsufficiency A20: A review of the literature
Florian Berteau,B. Rouviere,Aurélien Delluc,A. Nau,Rozenn Le Berre,Guillaume Sarrabay,Isabelle Touitou,Claire de Moreuil +7 more
TL;DR: High fever flares and digestive involvement starting in early childhood seem to be hallmarks of HA20 clinical features and biotherapies like anti-TNFα and anti IL1 appear to be treatments of choice, like for other auto-inflammatory diseases.
Journal ArticleDOI
Anti-tumor immunotherapy via antigen delivery from a live attenuated genetically engineered Pseudomonas aeruginosa type III secretion system-based vector.
Olivier Epaulard,Bertrand Toussaint,Lauriane E. Quenee,Madiha Derouazi,Nabil Bosco,Christian L. Villiers,Rozenn Le Berre,Benoit Guery,Didier Filopon,Laurence Crombez,Patrice N. Marche,Benoît Polack +11 more
TL;DR: In a curative assay, injection of the vaccine vector 5 and 12 days after tumor implantation led to a complete cure in five of six animals, highlighting the utility of type III secretion system-based vectors for anti-tumor immunotherapy.