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Ru Yan

Researcher at University of Macau

Publications -  82
Citations -  2590

Ru Yan is an academic researcher from University of Macau. The author has contributed to research in topics: Mass spectrometry & Colitis. The author has an hindex of 29, co-authored 75 publications receiving 2085 citations. Previous affiliations of Ru Yan include China Pharmaceutical University & The Chinese University of Hong Kong.

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Gut microbiota-involved mechanisms in enhancing systemic exposure of ginsenosides by coexisting polysaccharides in ginseng decoction

Shan-Shan Zhou, +15 more
- 02 Mar 2016 - 
TL;DR: Results indicated that ginseng polysaccharides improved intestinal metabolism and absorption of certain ginsenosides, meanwhile reinstated the perturbed holistic gut microbiota, and particularly enhanced the growth of Lactobacillus spp.
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Saikosaponin a and its epimer saikosaponin d exhibit anti-inflammatory activity by suppressing activation of NF-κB signaling pathway

Chunni Lu, +6 more
- 01 Sep 2012 - 
TL;DR: SSa and SSd showed potent anti-inflammatory activity through inhibitory effects on NF-κB activation and thereby on iNOS, COX-2 and pro-inflammatory cytokines.
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Enhanced topical penetration, system exposure and anti-psoriasis activity of two particle-sized, curcumin-loaded PLGA nanoparticles in hydrogel

Lin Sun, +8 more
- 28 May 2017 - 
TL;DR: E encapsulation of Cur into PLGA NPs, particularly for NPs of 50 nm, could facilitate lipophilic Cur's dispersion, sustained‐release, accumulation, and penetration across the skin and into the blood circulation, which significantly improves anti‐psoriasis activity in mice.
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Pharmacokinetics and Metabolism of Ligustilide, a Major Bioactive Component in Rhizoma Chuanxiong, in the Rat

Ru Yan, +4 more
- 01 Feb 2008 - 
TL;DR: Seven metabolites of ligustilide were identified, and three of them were unequivocally characterized as butylidenephthalide, senky unolide I, and senkyunolide H, which occurred naturally in the herb and were reported to be bioactive.
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Simultaneous analysis of seventeen chemical ingredients of Ligusticum chuanxiong by on-line high performance liquid chromatography-diode array detector-mass spectrometry.

Song Lin Li, +6 more
- 01 May 2003 - 
TL;DR: This is the first report to describe the development of an on-line HPLC-DAD-MS method to simultaneously analyse seventeen main constituents present in Chuanxiong and to construct the chemical profiles of various ChuanXiong samples.