R
Ruchi Singh
Researcher at University of Lucknow
Publications - 9
Citations - 99
Ruchi Singh is an academic researcher from University of Lucknow. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 3, co-authored 6 publications receiving 31 citations.
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Vibrational spectroscopic, NBO, AIM, and multiwfn study of tectorigenin: A DFT approach
TL;DR: Tectorigenin (5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one), a plant isoflavonoid, is a potential bioactive compound having antioxidant, antiinflammatory, antiosteoarthritis, anti-microbiotic, and antiplatelet activity.
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Investigating 11 Withanosides and Withanolides by UHPLC-PDA and Mass Fragmentation Studies from Ashwagandha (Withania somnifera).
Aboli Girme,Ganesh Saste,Sandeep Pawar,Arun Kumar Balasubramaniam,Kalpesh Musande,Bhaumik Darji,Naresh Kumar Satti,Mahendra K. Verma,Rajneesh Anand,Ruchi Singh,Ram A. Vishwakarma,Lal Hingorani +11 more
TL;DR: The WS extract from the root was subjected to ultrahigh-performance liquid chromatography with photodiode array detection (UHPLC–PDA) analysis to separate 11 withanoside and withanolide compounds and quantified and validated along with bioactive compounds simultaneously in WS.
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Inhibition of cartilage degeneration and subchondral bone deterioration by Spinacia oleracea in human mimic of ACLT-induced osteoarthritis
Priyanka Kothari,Shradha Sinha,Shradha Sinha,Anirban Sardar,Anirban Sardar,Ashish Kumar Tripathi,Aboli Girme,Sulekha Adhikary,Ruchi Singh,Rakesh Maurya,Prabhat Ranjan Mishra,Lal Hingorani,Ritu Trivedi,Ritu Trivedi +13 more
TL;DR: It is suggested that SOE has therapeutic potential, which if taken regularly as a food supplement, can have beneficial effects.
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Pharmacokinetic Study of Withanosides and Withanolides from Withania somnifera Using Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry (UHPLC-MS/MS)
Siddharth J. Modi,Anshul Tiwari,Chetana Ghule,Sandeep Pawar,Ganesh Saste,Shubham Jagtap,Ruchi Singh,Amol Deshmukh,Aboli Girme,Lal Hingorani +9 more
TL;DR: In this article , a rapid, selective, and reproducible bioanalytical method was developed and validated for seven withanosides and withanolides as per USFDA/EMA guidelines, further applied to determine pharmacokinetic parameters of Withania somnifera root extract (WSE) constituents in male Sprague Dawley rats.
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Caviunin glycoside (CAFG) from Dalbergia sissoo attenuates osteoarthritis by modulating chondrogenic and matrix regulating proteins.
Priyanka Kothari,Ashish Kumar Tripathi,Aboli Girme,Divya Rai,Ruchi Singh,Shradha Sinha,Dharmendra Choudhary,Geet Kumar Nagar,Rakesh Maurya,Lal Hingorani,Ritu Trivedi +10 more
TL;DR: In this article, the potential of Dalbergia sissoo DC leaves and its derived novel compound CAFG to treat the clinical symptoms of osteoarthritis and its underlying mechanism was studied.