Rusan Catar

TL;DR: Functional autoimmunity directed at AT1R and ETAR is common in patients with SSc and could contribute to disease pathogenesis and may serve as biomarkers for risk assessment of disease progression.

TL;DR: It is concluded that VAS2870 could provide a novel strategy to inhibit the augmented endothelial superoxide anion formation in response to cardiovascular risk factors.

TL;DR: It is argued that the differences of fresh and thawed MSCs are limited but significant, and recommended refocusing therapeutic MSC development on potency and safety assays with close resemblance of the clinical reality.

TL;DR: In this paper, a safety follow-up on placenta-derived decidual stromal cells (DSCs), used as supportive immunomodulatory and regenerative therapy for patients with severe complications after allogeneic hematopoietic stem cell transplantation (HSCT), was presented.

TL;DR: Better understanding of similarities and dissimilarities in HLA-DSA and distinct non-HLA antibody-related mechanisms of endothelial damage should facilitate discovery of common downstream signaling targets and pave the way for the development of endothelium-centered therapeutic strategies to accompany intensified immunosuppression and/or mechanical removal of antibodies.