R
Russell D. Schmidt
Researcher at University of Texas MD Anderson Cancer Center
Publications - 17
Citations - 1527
Russell D. Schmidt is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Virus & Feline immunodeficiency virus. The author has an hindex of 13, co-authored 17 publications receiving 1504 citations. Previous affiliations of Russell D. Schmidt include University of Zurich.
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Journal ArticleDOI
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection.
Timothy W. Baba,Vladimir Liska,Regina Hofmann-Lehmann,Josef Vlasak,Weidong Xu,Seyoum Ayehunie,Lisa A. Cavacini,Marshall R. Posner,Hermann Katinger,Gabriela Stiegler,Bruce J. Bernacky,Tahir A. Rizvi,Russell D. Schmidt,Lorraine R Hill,Michale E. Keeling,Yichen Lu,Joel E. Wright,Ting-Chao Chou,Ruth M. Ruprecht +18 more
TL;DR: It is concluded that epitopes recognized by the three monoclonal antibodies are important determinants for achieving substantial protection, thus providing a rational basis for AIDS vaccine development.
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Postnatal Passive Immunization of Neonatal Macaques with a Triple Combination of Human Monoclonal Antibodies against Oral Simian-Human Immunodeficiency Virus Challenge
Regina Hofmann-Lehmann,Josef Vlasak,Robert A. Rasmussen,Beverly A. Smith,Timothy W. Baba,Timothy W. Baba,Vladimir Liska,Flavia Ferrantelli,David C. Montefiori,Harold M. McClure,Daniel C. Anderson,Bruce J. Bernacky,Tahir A. Rizvi,Russell D. Schmidt,Lori R. Hill,Michale E. Keeling,Hermann Katinger,Gabriela Stiegler,Lisa A. Cavacini,Lisa A. Cavacini,Marshall R. Posner,Marshall R. Posner,Ting-Chao Chou,Janet Andersen,Ruth M. Ruprecht +24 more
TL;DR: Combined immunoprophylaxis with passively administered synergistic human MAbs may play a role in the clinical prevention of mother-to-infant transmission of HIV type 1.
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Primate and feline lentivirus vector RNA packaging and propagation by heterologous lentivirus virions.
TL;DR: The testing of the ability of FIV RNA to get cross-packaged into primate lentivirus particles such as HIV-1 and SIV, as well as a nonlentiviral retrovirus such as Mason-Pfizer monkey virus (MPMV), and vice versa reveals that diverse retroviruses are functionally more similar than originally thought.
Journal ArticleDOI
Postnatal pre- and postexposure passive immunization strategies: protection of neonatal macaques against oral simian-human immunodeficiency virus challenge.
Regina Hofmann-Lehmann,Josef Vlasak,Robert A. Rasmussen,Shisong Jiang,P.-L. Li,Timothy W. Baba,David C. Montefiori,Bruce J. Bernacky,Tahir A. Rizvi,Russell D. Schmidt,Lorraine R Hill,Michale E. Keeling,Hermann Katinger,Gabriela Stiegler,Lisa A. Cavacini,Marshall R. Posner,Ruth M. Ruprecht +16 more
TL;DR: The large‐scale use of passive immunization with neutralizing mAbs may be feasible in human neonates as it has promise to prevent intrapartum as well as milk‐borne virus transmission from HIV‐1‐infected women to their infants.
Journal ArticleDOI
Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies.
Ruth M. Ruprecht,Regina Hofmann-Lehmann,B. A. Smith-Franklin,Robert A. Rasmussen,Vladimir Liska,Josef Vlasak,Weidong Xu,Timothy W. Baba,Timothy W. Baba,Agnès-Laurence Chenine,Lisa A. Cavacini,Marshall R. Posner,Hermann Katinger,Gabriela Stiegler,Bruce J. Bernacky,Tahir A. Rizvi,Russell D. Schmidt,Lorraine R Hill,Michale E. Keeling,David C. Montefiori,Harold M. McClure +20 more
TL;DR: The triple mAb combination significantly protected the neonates, even against mucosal challenge with pathogenic SHIV89.6P, and it is concluded that the epitopes recognized by the mAbs in the authors' combinations are important for AIDS vaccine development.