S Fortini

TL;DR: Modifications to the hemodynamics in the left ventricle, when the inflow through the mitral orifice is altered, were investigated in vitro using a silicone rubber, flexible ventricular model and analysis of the turbulence statistics shows that the monoleaflet valves yield higher turbulence intensity in comparison with the bileaflet and, with top hat inflow, there is not a complete transition to turbulence.

TL;DR: In this article, the authors investigated the role of the fluid dynamics in the cardiac function and support the interpretation of the data obtained in vivo using a laboratory model, where the ventricle was simulated by a flexible sack varying its volume in time according to a physiologically shaped law, and velocities measured during several cycles on series of parallel planes, taken from two orthogonal points of view, were combined together to reconstruct the phase-averaged, three-dimensional velocity field.

TL;DR: A quantitative comparison of the phase-averaged velocity and vorticity fields between the simulation and the experiment shows a reasonable agreement, which is used to identify and discuss the key challenges that are faced in such a validation study.

TL;DR: Three-dimensional data gives the experimental evidence of the reorganization of the flow in a single vortex persisting until the end of the diastole, which seems to optimize the cardiac function since it directs velocity towards the aortic valve just before the systole and minimizes the fraction of blood residing within the ventricle for more cycles.

TL;DR: In this paper, the authors used Lagrangian Coherent Structure time evolution and flow dispersion properties to verify the asymmetric structure of the ventricular filling in two orthogonal views.