S. S. Soares

TL;DR: The effects of equal doses of two different metals intravenously injected in the same fish species and upon the same exposure period are described for the first time to understand the mechanisms of vanadate and cadmium toxicity in fish cardiac muscle.

TL;DR: Decavadate has a different response pattern of lipid peroxidation and oxidative stress markers, in spite of the same vanadium distribution in cardiac cells observed after decavanadate and metavanadates administration.

TL;DR: Investigation of the toxicity to neonatal rat ventricular myocytes of two vanadate solutions containing different oligovanadates distribution found mitochondrial membrane depolarization was an early event in decavanadates- and monovanadate-induced necrotic cell death of cardiomyocytes.

TL;DR: It is concluded that decavanadate is much more potent mitochondrial depolarization agent and a more potent inhibitor of mitochondrial oxygen consumption than monomeric vanadate, pointing out the importance to take into account the contribution of higher oligomeric species of vanadium for the biological effects ofVanadate solutions.

TL;DR: Decameric vanadates administration clearly induces different effects than the other vanadate oligomeric species, pointing out the importance of taking into account the different vanADate oligomers in the evaluation of vanadium(V) effects in biological systems.