S
Sabrina C. Desbordes
Researcher at Pompeu Fabra University
Publications - 2
Citations - 516
Sabrina C. Desbordes is an academic researcher from Pompeu Fabra University. The author has contributed to research in topics: Cell Transdifferentiation & Cell. The author has an hindex of 2, co-authored 2 publications receiving 472 citations.
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Journal ArticleDOI
PU.1 and C/EBPα/β convert fibroblasts into macrophage-like cells
Ru Feng,Sabrina C. Desbordes,Huafeng Xie,Ester Sanchez Tillo,Fiona J. Pixley,E. Richard Stanley,Thomas Graf,Thomas Graf +7 more
TL;DR: The data suggest that it might become possible to induce the transdifferentiation of skin-derived fibroblasts into cell types desirable for tissue regeneration, and the effects of PU.1 and C/EBPα on fibro Blasts are examined.
Journal ArticleDOI
A Robust and Highly Efficient Immune Cell Reprogramming System
Lars H. Bussmann,Alexis Schubert,Thien Phong Vu Manh,Luisa I. De Andres,Sabrina C. Desbordes,Maribel Parra,Timo Zimmermann,Francesca Rapino,Javier Rodríguez-Ubreva,Esteban Ballestar,Thomas Graf +10 more
TL;DR: A lineage reprogramming system consisting of a B cell line with an estradiol-inducible form of C/EBPalpha where cells can be converted into macrophage-like cells at 100% efficiency within 2 to 3 days is described.