S
Sacha B. Nelson
Researcher at Brandeis University
Publications - 140
Citations - 30371
Sacha B. Nelson is an academic researcher from Brandeis University. The author has contributed to research in topics: Visual cortex & Excitatory postsynaptic potential. The author has an hindex of 68, co-authored 134 publications receiving 27897 citations. Previous affiliations of Sacha B. Nelson include Salk Institute for Biological Studies & Center for Neural Science.
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Journal ArticleDOI
Multi-unit spike-triggered averaging: a method for probing the physiology of central synapses
TL;DR: Since it requires only a single intracellular recording, multi-unit STA might be a suitable method for probing unitary synaptic connections in the intact brain, where obtaining multiple intrACEllular recordings is not feasible.
Posted Content
Cell-type-specific transcriptomes and the Allen Atlas (II): discussion of the linear model of brain-wide densities of cell types
Pascal Grange,Jason W. Bohland,Benjamin W. Okaty,Ken Sugino,Hemant Bokil,Sacha B. Nelson,Lydia Ng,Michael Hawrylycz,Partha P. Mitra +8 more
TL;DR: The voxelized Allen Atlas of the adult mouse brain is used in [arXiv:1303.0013] to estimate the region-specificity of 64 cell types whose transcriptional profile in the mouse brain has been measured in microarray experiments, and the model yields estimates for the brain-wide density of each of these cell types.
Journal ArticleDOI
Timing isn't everything.
TL;DR: Oertel et al. as discussed by the authors found quantal inhibitory postsynaptic currents (IPSCs) evoked the bushy cells that receive auditory nerve input via at low frequency were identical to the kinetics of miniamassive synapses called calyces or end bulbs.
Journal ArticleDOI
Effects of luminance and flicker on ocular dominance shift in kitten visual cortex.
TL;DR: It is concluded that dim flickering light is not a sufficient stimulus for promoting ocular dominance shift in kittens in the critical period unless the flicker rate approaches 0.1 Hz, and results from the TV rearing suggest that flicker may be capable of preventing an ocular dominated shift expected from a concurrent steady low light level background.
Book ChapterDOI
Electrotonic Structure and Synaptic Variability in Cortical Neurons
D. K. Smetters,Sacha B. Nelson +1 more
TL;DR: Varying the peak synaptic conductance independent of location is sufficient to match the experimental distributions of all of these parameters, without interfering with the fit of the voltage-clamp distributions.