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Sainan Li
Researcher at Westlake University
Publications - Â 5
Citations - Â 1070
Sainan Li is an academic researcher from Westlake University. The author has contributed to research in topics: Platelet degranulation & Immunosuppression. The author has an hindex of 3, co-authored 5 publications receiving 574 citations.
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Journal ArticleDOI
Proteomic and Metabolomic Characterization of COVID-19 Patient Sera.
Bo Shen,Xiao Yi,Yaoting Sun,Xiaojie Bi,Juping Du,Chao Zhang,Sheng Quan,Fangfei Zhang,Rui Sun,Liujia Qian,Weigang Ge,Wei Liu,Shuang Liang,Hao Chen,Ying Zhang,Jun Li,Jiaqin Xu,Zebao He,Baofu Chen,Jing Wang,Haixi Yan,Yufen Zheng,Donglian Wang,Jiansheng Zhu,Ziqing Kong,Zhouyang Kang,Xiao Liang,Xuan Ding,Guan Ruan,Nan Xiang,Xue Cai,Huanhuan Gao,Lu Li,Sainan Li,Qi Xiao,Tian Lu,Yi Zhu,Huafen Liu,Haixiao Chen,Tiannan Guo +39 more
TL;DR: This study revealed characteristic protein and metabolite changes in the sera of severe COVID-19 patients, which might be used in selection of potential blood biomarkers for severity evaluation.
Posted ContentDOI
Proteomic and Metabolomic Characterization of COVID-19 Patient Sera
Bo Shen,Xiao Yi,Yaoting Sun,Xiaojie Bi,Juping Du,Chao Zhang,Sheng Quan,Fangfei Zhang,Rui Sun,Liujia Qian,Weigang Ge,Wei Liu,Shuang Liang,Hao Chen,Ying Zhang,Jun Li,Jiaqin Xu,Zebao He,Baofu Chen,Jing Wang,Haixi Yan,Yufen Zheng,Donglian Wang,Jiansheng Zhu,Ziqing Kong,Zhouyang Kang,Xiao Liang,Xuan Ding,Guan Ruan,Nan Xiang,Xue Cai,Huanhuan Gao,Lu Li,Sainan Li,Qi Xiao,Tian Lu,Yi Zhu,Huafen Liu,Haixiao Chen,Tiannan Guo +39 more
TL;DR: This study shows that it is possible to predict progression to severe CO VID-19 disease using serum protein and metabolite biomarkers and uncovered molecular pathophysiology of COVID-19 with potential for developing anti-viral therapies.
Posted ContentDOI
Proteomics Uncovers Immunosuppression in COVID-19 Patients with Long Disease Course
Shaohua Tang,Rui Sun,Qi Xiao,Tingting Mao,Weigang Ge,Chongquan Huang,Meng Luo,Meng Luo,Liujia Qian,Hao Chen,Qiushi Zhang,Sainan Li,Wei Liu,Wei Liu,Shufen Li,Xueqin Xu,Huangzheng Li,Lianpeng Wu,Jianyi Dai,Huanhuan Gao,Lu Li,Tian Lu,Xiao Liang,Xue Cai,Guan Ruan,Kexin Liu,Fei Xu,Yan Li,Yi Zhu,Jianping Huang,Tiannan Guo +30 more
TL;DR: A rich serum proteomic resource is presented to understand host responses in COVID-19 patients and characteristic Treg-mediated immunosuppression in LC patients is identified, nominating new therapeutic target and diagnosis strategy.
Journal ArticleDOI
Proteomic and Metabolomic Characterization of COVID-19 Patient Sera
Bo Shen,Xiao Yi,Yaoting Sun,Xiaojie Bi,Juping Du,Chao Zhang,Sheng Quan,Fangfei Zhang,Rui Sun,Liujia Qian,Weigang Ge,Wei Liu,Shuang Liang,Hao Chen,Ying Zhang,Jun Li,Jiaqin Xu,Zebao He,Baofu Chen,Jing Wang,Haixi Yan,Yufen Zheng,Donglian Wang,Jiansheng Zhu,Ziqing Kong,Zhouyang Kang,Xiao Liang,Xuan Ding,Guan Ruan,Nan Xiang,Xue Cai,Huanhuan Gao,Lu Li,Sainan Li,Qi Xiao,Tian Lu,Yi Zhu,Huafen Liu,Haixiao Chen,Tiannan Guo +39 more
TL;DR: This study shows that it is possible to predict progression to severe CO VID-19 disease using serum protein and metabolite biomarkers and uncovered molecular pathophysiology of COVID-19 with potential for developing anti-viral therapies.
Journal ArticleDOI
Proteomics Uncovers Immunosuppression in COVID-19 Patients with Long Disease Course
Shaohua Tang,Rui Sun,Qi Xiao,Tingting Mao,Weigang Ge,Chongquan Huang,Meng Luo,Liujia Qian,Hao Chen,Qiushi Zhang,Sainan Li,Wei Liu,Wei Liu,Shufen Li,Xueqin Xu,Huangzheng Li,Lianpeng Wu,Jianyi Dai,Huanhuan Gao,Lu Li,Tian Lu,Xiao Liang,Xue Cai,Guan Ruan,Kexin Liu,Fei Xu,Yan Li,Yi Zhu,Jianping Huang,Tiannan Guo +29 more
TL;DR: A rich serum proteomic resource is presented to understand host responses in COVID-19 patients and characteristic Treg-mediated immunosuppression in LC patients is identified, nominating new therapeutic target and diagnosis strategy.