Saleem S. Qader

TL;DR: In this article, the effects of the proghrelin products, alone and in combinations, on the secretion of insulin, glucagon, pancreatic polypeptide (PP) and somatostatin from isolated islets of mice and rats were examined.

TL;DR: The present results confirm the previous data showing that ghrelin inhibits insulin and stimulates glucagon secretion from pancreatic islets of the mouse and shows similar effects in rat islets, and suggest that ncNOS activation partly accounts for to the inhibitory effect of gh Relin on insulin secretion and the stimulatory effect ofghrelin on glucagons secretion.

TL;DR: The results support the idea that neural ATP signals entrain the islets into a common rhythm resulting in pulsatile release of insulin and that glucose stimulation of the secretory activity is counteracted by accumulation of inhibitory ATP around the beta-cells.

TL;DR: Analysis of 30 s fractions from the perfused rat pancreas indicated that increase of glucose from 3 to 20 mmol/l results in initial suppression of somatostatin release followed by regular 4-5 min pulses, supporting the idea that the delta-cells have a local inhibitory effect on glucagon release.

TL;DR: In this paper, the radon alpha activity concentration has been measured in 28 homes in the Erbil Capital-Iraqi Kurdistan region during the autumn season by using time-integrated passive radon dosimeters containing CR-39 solid state nuclear track detectors.