S
Salvatore Profeta
Researcher at Florida State University
Publications - 26
Citations - 4898
Salvatore Profeta is an academic researcher from Florida State University. The author has contributed to research in topics: Ab initio & Ab initio quantum chemistry methods. The author has an hindex of 15, co-authored 26 publications receiving 4798 citations. Previous affiliations of Salvatore Profeta include University of California, San Francisco & Monsanto.
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Journal ArticleDOI
A new force field for molecular mechanical simulation of nucleic acids and proteins
S. J. Weiner,Peter A. Kollman,David A. Case,U. C. Singh,Caterina Ghio,Giuliano Alagona,Salvatore Profeta,Paul K. Weiner +7 more
TL;DR: In this paper, a force field for simulation of nucleic acids and proteins is presented, which is based on the ECEPP, UNECEPP, and EPEN energy refinement software.
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Origins of Selectivity for the [2+2] Cycloaddition of α,β-unsaturated Ketones within a Porous Self-assembled Organic Framework
TL;DR: In this paper, the origins of selectivity for α,β-unsaturated ketones within a porous crystalline host were investigated. But the authors focused on the 3-methyl-2-cyclopentenone and 2-cyclohexenone.
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A distance geometry study of ring systems
Paul K. Weiner,Salvatore Profeta,Georges Wipff,Timothy F. Havel,Irwin D. Kuntz,Robert Langridge,Peter A. Kollman +6 more
TL;DR: In this paper, the authors applied distance geometry methods to the generation of structures of a sampling of organic molecules: cyclooctane, cyclododecane, 18-crown-6, and androstane-3,17-dione.
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Mechanism of Initiation in the Phillips Ethylene Polymerization Catalyst: Redox Processes Leading to the Active Site
Carole Brown,J. Krzystek,Randall Achey,Adrian Lita,Riqiang Fu,Robert W. Meulenberg,Matthew J. Polinski,Nathan Peek,Youhong Wang,Lambertus J. van de Burgt,Salvatore Profeta,Albert E. Stiegman,Susannah L. Scott +12 more
TL;DR: In this article, a mesoporous, optically transparent monolith of CrVI/SiO2 was prepared using sol-gel chemistry in order to monitor the reduction process spectroscopically.
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Synthesis, Topoisomerase I Inhibitory Activity, and in Vivo Evaluation of 11-Azacamptothecin Analogs
David E. Uehling,Nanthakumar Ss,Dallas K. Croom,David L. Emerson,Leitner Pp,Michael Joseph Luzzio,Gordon McIntyre,Bradley Morton,Salvatore Profeta,Sisco J +9 more
TL;DR: A series of analogs based on a novel template, 11-aza-(20S)-camptothecin, were obtained from total synthesis and tested as potential anticancer drugs in the topoisomerase I enzyme cleavable complex assay and proved to be effective in whole cell cytotoxicity assays.