S
Samantha Cooper
Researcher at University of Nottingham
Publications - 17
Citations - 105
Samantha Cooper is an academic researcher from University of Nottingham. The author has contributed to research in topics: Sunitinib & Cardiotoxicity. The author has an hindex of 4, co-authored 13 publications receiving 52 citations. Previous affiliations of Samantha Cooper include Coventry University & Coventry Health Care.
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Journal ArticleDOI
Role of the Renin-Angiotensin-Aldosterone and Kinin-Kallikrein Systems in the Cardiovascular Complications of COVID-19 and Long COVID.
Samantha Cooper,Eleanor Boyle,Sophie R. Jefferson,Calum R. A. Heslop,Pirathini Mohan,Gearry G. J. Mohanraj,Hamza A. Sidow,Rory C. P. Tan,Stephen J. Hill,Jeanette Woolard +9 more
TL;DR: In this article, the authors reviewed the impact of COVID-19 on the cardiovascular system, the mechanisms by which dysregulation of the RAAS and KKS can occur following virus infection and the future implications for pharmacological therapies.
Journal ArticleDOI
Involvement of mitogen activated kinase kinase 7 intracellular signalling pathway in Sunitinib-induced cardiotoxicity.
TL;DR: Investigation into the ASK1/MKK7/JNK transduction pathway could lead to development of cardioprotective adjunct therapy, which could prevent Sunitinib-induced cardiotoxicity.
Journal ArticleDOI
Attenuation of Sunitinib-induced cardiotoxicity through the A3 adenosine receptor activation
TL;DR: It is revealed that A3 adenosine receptor activation by IB‐MECA attenuates Sunitinib‐induced cardiotoxicity through the involvement of PKC&agr;.
Journal ArticleDOI
Probe dependence of allosteric enhancers on the binding affinity of adenosine A 1 -receptor agonists at rat and human A 1 -receptors measured using NanoBRET
Samantha Cooper,Samantha Cooper,Mark Soave,Mark Soave,Manuela Jörg,Peter J. Scammells,Jeanette Woolard,Jeanette Woolard,Stephen J. Hill,Stephen J. Hill +9 more
TL;DR: This work investigates the species and probe dependence of two allosteric modulators on the binding characteristics of fluorescent and nonfluorescent A1‐receptor agonists.
Journal ArticleDOI
The effect of two selective A1 -receptor agonists and the bitopic ligand VCP746 on heart rate and regional vascular conductance in conscious rats.
Samantha Cooper,Samantha Cooper,Julie E. March,Julie E. March,Andrea R. Sabbatini,Andrea R. Sabbatini,Stephen J. Hill,Stephen J. Hill,Manuela Jörg,Peter J. Scammells,Jeanette Woolard,Jeanette Woolard +11 more
TL;DR: The effect of two A1‐receptor‐selective agonists and the novel A1-receptor bitopic ligand VCP746 on the rat cardiovascular system is investigated.