Samantha Mattioli

TL;DR: In this article, different results on the fabrication of nanocomposites based on biodegradable polymers for specific field of tissue engineering are presented, and the combination of bioresorbable polymer and nanostructures open new perspectives in the self-assembly of nanomaterials for biomedical applications with tuneable mechanical, thermal and electrical properties.

TL;DR: In this article, the promising prospects of poly(lactic acid) based nanostructured materials considering two main potential uses, packaging and tissue engineering, are reported, and a comprehensive analysis of the recent advances in tissue engineering applications focusing in the synthesis of PLA nanoparticles, the processing of PLA based multifunctional nanocomposites and PLA surface modification techniques.

TL;DR: The paper describes antibacterial effects due to the induced material properties, along with the principles of bacterial adhesion and the biofilm formation process, and presents an outline of future sceneries and perspectives on antibacterial applications of nanostructured materials to resist or counteract implant infections.

TL;DR: It is demonstrated that the surface topography with micropatterned nanoridge width/spacing of 40/30μm (single stimulus) induced hBM-MSCs to acquire neuronal characteristics in the absence of differentiating agents, suggesting the occurrence of a mechanotransducer effect exerted by optimal nano/microstructure dimensions on the hBM -MSCs responses.

TL;DR: This study explored the interface between human bone marrow-derived mesenchymal stem cells (hBM-MSCs) and hydrogenated amorphous carbon (a-C:H) film designed with uniform, groove, or grid nanopatterns, suggesting that the films were biocompatible and suitable for stem cell culture.