Francesco D'Angelo

TL;DR: In this review, the challenges behind translating stem cell biology and biomaterial innovations into novel clinical therapeutic applications for tissue and organ replacements are reported on.

TL;DR: Compared to the 4th and the 5th-6th TNM editions, the simplicity and easy application of the new stadiation and the better prognostic stratification of the N-stage are confirmed, and 10 lymph nodes in early gastric cancer and at least 16 in the other pT-stages seem sufficient for a real pN0 stadiated.

TL;DR: In this paper, the combination of single walled carbon nanotubes (SWCNTs) and silver nanoparticles (Ag) with a biodegradable polymer matrix was evaluated in terms of morphological, electrical, dielectrical, mechanical and biological properties.

TL;DR: Results indicate that the osteogenic differentiation effect of these electrospun PLLA/d-HAp nanocomposites was independent of the stem cell type and highlight the direct interaction of stem cell-polymeric nanocomPOSite and the mechanical properties acquired by the PLL a/d -HAp Nanocomposite as key steps for the differentiation process.

TL;DR: It is demonstrated that the surface topography with micropatterned nanoridge width/spacing of 40/30μm (single stimulus) induced hBM-MSCs to acquire neuronal characteristics in the absence of differentiating agents, suggesting the occurrence of a mechanotransducer effect exerted by optimal nano/microstructure dimensions on the hBM -MSCs responses.