S
Sami Nummelin
Researcher at Aalto University
Publications - 41
Citations - 2714
Sami Nummelin is an academic researcher from Aalto University. The author has contributed to research in topics: Dendrimer & DNA origami. The author has an hindex of 19, co-authored 40 publications receiving 2320 citations. Previous affiliations of Sami Nummelin include University of Pennsylvania & University of Jyväskylä.
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Journal ArticleDOI
Self-Assembly of Janus Dendrimers into Uniform Dendrimersomes and Other Complex Architectures
Virgil Percec,Daniela A. Wilson,Pawaret Leowanawat,Christopher J. Wilson,Andrew D. Hughes,Mark S. Kaucher,Daniel A. Hammer,Dalia H. Levine,Anthony J. Kim,Frank S. Bates,Kevin P. Davis,Timothy P. Lodge,Michael L. Klein,Russell DeVane,Emad Aqad,Brad M. Rosen,Andreea O. Argintaru,Monika J. Sienkowska,Kari Rissanen,Sami Nummelin,Sami Nummelin,Jarmo Ropponen +21 more
TL;DR: Dendrimersomes marry the stability and mechanical strength obtainable from polymersomes with the biological function of stabilized phospholipid liposomes, plus superior uniformity of size, ease of formation, and chemical functionalization, providing access to systematic tuning of molecular structure and of self-assembled architecture.
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Self-assembly of amphiphilic dendritic dipeptides into helical pores
Virgil Percec,Andrés E. Dulcey,Venkatachalapathy S. K. Balagurusamy,Yoshiko Miura,Jan Smidrkal,Mihai Peterca,Sami Nummelin,Ulrica Edlund,Steven D. Hudson,Paul A. Heiney,H. Duan,Sergei Magonov,Sergei A. Vinogradov +12 more
TL;DR: A library of amphiphilic dendritic dipeptides that self-assemble in solution and in bulk through a complex recognition process into helical pores is described, finding that the molecular recognition and self-assembly process is sufficiently robust to tolerate a range of modifications to the amphiphile structure.
Journal ArticleDOI
Protein Coating of DNA Nanostructures for Enhanced Stability and Immunocompatibility.
Henni Auvinen,Hongbo Zhang,Hongbo Zhang,Nonappa,Alisa Kopilow,Elina H. Niemelä,Sami Nummelin,Alexandra Correia,Hélder A. Santos,Veikko Linko,Mauri A. Kostiainen +10 more
TL;DR: The results reveal that BSA‐coating significantly improves the origami stability against endonucleases (DNase I) and enhances the transfection into human embryonic kidney (HEK293) cells and attenuates the activation of immune response in mouse primary splenocytes.
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Evolution of Structural DNA Nanotechnology
TL;DR: This Progress Report summarizes how the controllable, custom, and accurate nanostructures have recently evolved together with powerful design and simulation software to provide a significant expansion of the shape space of the nanostructure.
Journal ArticleDOI
Generic Method for Modular Surface Modification of Cellulosic Materials in Aqueous Medium by Sequential “Click” Reaction and Adsorption
Ilari Filpponen,Eero Kontturi,Sami Nummelin,Henna Rosilo,Erkki Kolehmainen,Olli Ikkala,Janne Laine +6 more
TL;DR: The concept by sequentially combining the robust physical adsorption and robust chemical reaction allows versatile, simple, and environmentally friendly modification of a cellulosic substrate with virtually any azide- or alkyne-modified molecule and even functionalization with several types of units.